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临床试验/NCT03468738
NCT03468738已完成不适用

Investigation of the Transfusion Practices in Surgical Patients in Turkey

Diskapi Teaching and Research Hospital61 个研究点 分布在 1 个国家目标入组 6,481 人开始时间: 2018年4月2日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
6,481
试验地点
61
主要终点
Preoperative amount of blood products transfused

研究概览

简要总结

The aim of this study is to describe the transfusion practices in patients undergoing major surgery in Turkey. The transfusion rates of red blood cells (RBC), fresh frozen plasma (FFP) and platelets; the transfusion predictors and transfusion related patient outcomes are investigated.

详细描述

Patient Blood Management (PBM) is an evidence based multidisciplinary approach for the care of patients who may need blood transfusion. The aim of PBM is achieving better patient outcomes by focusing on the patients' own blood as a source.

To date PBM is considered "good transfusion practice" and is being implemented in a growing number of countries. The Turkish Society of Anesthesiologists PBM Task Force is working on this subject since 4 years and decided to conduct a study. Before starting a PBM program, the transfusion practices of clinicians working at diverse surgical fields; differences between current transfusion practices and PBM strategies; the areas for improvement and the obstacles that could prevent change could be identified with this study. Data collection will also serve to identify the current situation as a reference and to control the achievement of the PBM's aim: improving clinical outcomes. These data will be refered as The Turkish National Perioperative Transfusion Study (TULIP TS) data.

The aim of this study is to describe the transfusion practices in patients undergoing major surgery in Turkey.

The study evaluates i. The perioperative transfusion rates of RBCs, FFP and platelets. ii. With which reasons the anesthesiologists decide to transfuse a patient (co morbidities of the patients, physiologic transfusion triggers, hemoglobin trigger, uncontrolled bleeding, on request from surgeon etc.).

iii. The relation of transfusion and the patients co-morbidity index, the P POSSUM score and SORT score; anesthesia methods; monitorisation methods (hemodynamic, coagulation); amount of bleeding; type of surgery; type of hospital.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Patients undergoing major elective surgery

排除标准

  • Trauma patients, emergency surgery

结局指标

主要结局

Preoperative amount of blood products transfused

时间窗: Before surgery at day 0

Preoperative amount of blood products: RBCs,FFP and platelets transfused

Intraoperative amount of blood products transfused

时间窗: During surgery at day 0

Intraoperative amount of blood products: RBC's,FFP and platelets transfused

Postoperative amount of blood products transfused

时间窗: 24 hours after surgery

Postoperative amount of blood products: RBCs,FFP and platelets transfused

次要结局

  • Prolonged length of stay in ICU(After surgery at day 2)
  • Advers cardiac events(After surgery at day 30)
  • Acute renal failure(After surgery at day 2)
  • Ischemic event(After surgery at day 2)
  • Infection(After surgery at day 2)
  • Preoperative coagulopathy(Before surgery at day 0)
  • Intraoperative transfusion indications(During surgery at day 1)
  • Pretransfusion hemoglobin values(After surgery at day 2)
  • Mortality(after surgery at day 30)
  • Preoperative anemia(Before surgery at day 0)
  • Preoperative transfusion indications(Before surgery at day 0)
  • Postoperative transfusion indications(24 hours after surgery)
  • Unanticipated ICU admission(After surgery at day 1)
  • Thromboembolic event(After surgery at day 2)
  • Acute respiratory distress(After surgery at day 2)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

DILEK YAZICIOGLU

Associate Professor

Diskapi Teaching and Research Hospital

研究点 (61)

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