Effect of Osteoanabolic Exercises on Gait, Balance & Fear of Fall Among Osteoporotic Females

Not Applicable

Completed

• Conditions: Osteoporosis

• Registration Number: NCT04898218
• Lead Sponsor: Ziauddin University

Brief Summary

With the increase in life expectancy women spend more than one-third of their life time in post-menopausal state leading to osteoporosis in later stages. Therefore a decrease in temporal-spatial parameters of gait, high risk of fracture, imbalance in functional parameters, fear of fall and compromised health-related quality of life is observed among osteoporotic females. Several physical activities and balance training programs have been implemented globally but nationally no program has yet been designed catering gait balance and fear of fall altogether as a combined program. Therefore, the aim of this study was to determine the effectiveness of Osteoanabolic exercises on Temporal-Spatial gait parameters, Gait Stability Ratio (GSR) and Bone Mineral Density (BMD) among the osteoporotic females. Moreover, the effectiveness of these exercises was evaluated on dynamic balance using Timed Up and Go Test (TUG).

Furthermore, the impact on fear of fall was identified using Fall Efficacy ScaleInternational (FES-I).

Detailed Description

A 3-arm Randomized Controlled Trial was conducted at the Department of Rehabilitation Sciences, Ziauddin Hospital using the envelope method. The participants were screened on the Physical Activity Readiness and You Questionnaire (PARQ \&YOU). Ninety-three osteoporotic females were randomly allocated into three groups; where; participant in group A' received aerobic training protocol, a participant in group B' resistance training and participant in group C' Osteoanabolic training. A Frequency Intensity Time Type (FITT) protocol according to the American College of Sports Medicine for aerobic and resistance training was incorporated whereas for Osteoanabolic group combination training protocol was used. Twelve weeks of training was conducted where pre and post readings were calculated using activPAL, TUG, FES-I and Peripheral DXA Scan.

Study Timeline

• Study Start: 2017-10-02
• Primary Completion: 2018-11-21
• Study Completion: 2018-12-24
• Study First Submitted: 2020-12-22
• Status Verified: 2021-05
• Study First Submitted QC: 2021-05-21
• Last Update Submitted: 2021-05-21
• Study First Posted: 2021-05-24
• Last Update Posted: 2021-05-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 93

Inclusion Criteria

• Postmenopausal osteoporotic females aged in between 50-75 years
• Not participating in any exercise program for the past 3 months
• Independently ambulatory were included in the study

Exclusion Criteria

• Red flags that limit the recruitment of participants in an exercise program, for example, vertebral fracture, an unstable heart condition, malignancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Cadence	12 weeks	Temporal Spatial Gait Parameter
Gait Velocity	12 weeks	Temporal Spatial Gait Parameter
Gait Stability Ratio	12 weeks	Temporal Spatial Gait Parameter
Balance	12 weeks	Balance was measured through Timed-up and Go Test
Fear of Fall	12 weeks	Measured through Fall Efficacy Scale- International consisting of 16 items that are summed to calculate a total score from minimum 16 to maximum 64. Higher the score, greater the fear of falling.

Secondary Outcome Measures

Name	Time	Method
Bone Mineral Density	12 weeks	Measured through Peripheral DXA Scan on right side calcaneal bone

Trial Locations

Locations (1)

Ziauddin University; 🇵🇰 Karachi, Pakistan