The Effect of Exercise Intervention on the Community's Older Adults
- Conditions
- Metabolic Disease
- Interventions
- Other: exercise
- Registration Number
- NCT02936336
- Lead Sponsor
- Chang Gung Memorial Hospital
- Brief Summary
Osteoporosis is a serious global health problem, second only to cardiovascular disease. Osteoporosis is the most common metabolic bone disease in the elderly population, characterized by loss of bone mineral density (BMD) and continuous destruction of bone microstructure, especially in postmenopausal women. It gives rise to bone fragility and fracture risk. Moreover, as people grow older, falls frequently occur with high severity, and nearly 35% to 45% of persons aged 65 or older fall at least once a year. Osteoporotic fractures increase mortality, morbidity, chronic pain, and the cost of social care and it decreases the quality of life. Here, investigators plan to perform different exercise interventions such as circuit exercise, aerobic dance and Tai Chi on the community's older adults to evaluate whether exercise intervention could improve the bone mineral density, physical fitness, muscle strength or quality of life.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 411
- Being >45 years-of-age,
- Healthy and physically independent.
- The exclusion criteria were individuals on hormone replacement therapy and those with cognitive impairment, progressive debilitating conditions, bone fractures, or any medical contraindications to administering the fitness assessment.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Exercise exercise Subjects with circuit exercise, aerobic dance, or Tai Chi exercise intervention.
- Primary Outcome Measures
Name Time Method Change from baseline bone mineral density Pre-intervention, 3-month, 6-month, 9-month-follow-up Bone mineral density measurement is measured by dual-energy x-ray absorptiometry (DXA). Measurements are made over the lumbar spine and over the upper part of the hip and the measurement is assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
- Secondary Outcome Measures
Name Time Method Triglyceride from blood sample Pre-intervention, 3-month, 6-month, 9-month-follow-up Triglyceride are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Waistline parameters of the subjects Pre-intervention, 3-month, 6-month, 9-month-follow-up Waistline (cm) are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Change from baseline elbow muscle strength Pre-intervention, 3-month, 6-month, 9-month-follow-up Extension and flexion of elbow were tested by the HUMAC NORM system (CSMi, Stoughton, MA) with the eccentric/concentric contraction mode at an angular velocity of 60 degrees/s.Isokinetic tests were performed five times for each participant, and each test was separated by a rest period of 3 min.The Muscle strength was present as a peak torque which was normalized to body weight (Unit:Nm/kg). The participants are assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
High-density lipoprotein from blood sample Pre-intervention, 3-month, 6-month, 9-month-follow-up High-density lipoprotein are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Change from baseline shoulder muscle strength Pre-intervention, 3-month, 6-month, 9-month-follow-up Extension and flexion of shoulder were tested by the HUMAC NORM system (CSMi, Stoughton, MA) with the eccentric/concentric contraction mode at an angular velocity of 60 degrees/s.Isokinetic tests were performed five times for each participant, and each test was separated by a rest period of 3 min.The Muscle strength was present as a peak torque which was normalized to body weight (Unit:Nm/kg). The participants are assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Change from baseline hip muscle strength Pre-intervention, 3-month, 6-month, 9-month-follow-up Extension and flexion of hip were tested by the HUMAC NORM system (CSMi, Stoughton, MA) with the eccentric/concentric contraction mode at an angular velocity of 60 degrees/s.Isokinetic tests were performed five times for each participant, and each test was separated by a rest period of 3 min.The Muscle strength was present as a peak torque which was normalized to body weight (Unit:Nm/kg). The participants are assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Fasting blood glucose from blood sample Pre-intervention, 3-month, 6-month, 9-month-follow-up Fasting blood glucose are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Blood pressure Pre-intervention, 3-month, 6-month, 9-month-follow-up Diastolic and systolic blood pressure are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Weight parameters of the subjects Pre-intervention, 3-month, 6-month, 9-month-follow-up Weight (kg) are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Height parameters of the subjects Pre-intervention, 3-month, 6-month, 9-month-follow-up Height (cm) are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Change from baseline knee muscle strength Pre-intervention, 3-month, 6-month, 9-month-follow-up Extension and flexion of knee were tested by the HUMAC NORM system (CSMi, Stoughton, MA) with the eccentric/concentric contraction mode at an angular velocity of 60 degrees/s.Isokinetic tests were performed five times for each participant, and each test was separated by a rest period of 3 min.The Muscle strength was present as a peak torque which was normalized to body weight (Unit:Nm/kg). The participants are assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Change from baseline SF-36 questionnaire assessment Pre-intervention, 3-month, 6-month, 9-month-follow-up SF-36 consists of eight scaled scores, which are the weighted sums of the questions in their section. Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The lower score the more disability. The higher the score the less disability. Eight sections including physical function, role limitation due to physical problems, bodily pain, general health, vitality, social functioning, role limitation due to emotional problems, and mental health. Additionally, the eight health domains can be used to provide a physical component summary and mental component summary score. The outcome measurement is assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Trial Locations
- Locations (1)
Sports Medicine Center, Chang Gung Memorial Hospital
🇨🇳Pizi, Taiwan