The Effect of Exercise Intervention on the Physical Fitness, Bone Mineral Density and Health-related Quality of Life in the Community's Older Adults
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Metabolic Disease
- Sponsor
- Chang Gung Memorial Hospital
- Enrollment
- 411
- Locations
- 1
- Primary Endpoint
- Change from baseline bone mineral density
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
Osteoporosis is a serious global health problem, second only to cardiovascular disease. Osteoporosis is the most common metabolic bone disease in the elderly population, characterized by loss of bone mineral density (BMD) and continuous destruction of bone microstructure, especially in postmenopausal women. It gives rise to bone fragility and fracture risk. Moreover, as people grow older, falls frequently occur with high severity, and nearly 35% to 45% of persons aged 65 or older fall at least once a year. Osteoporotic fractures increase mortality, morbidity, chronic pain, and the cost of social care and it decreases the quality of life. Here, investigators plan to perform different exercise interventions such as circuit exercise, aerobic dance and Tai Chi on the community's older adults to evaluate whether exercise intervention could improve the bone mineral density, physical fitness, muscle strength or quality of life.
Investigators
Robert Wen-Wei Hsu
Honorary Dean
Chang Gung Memorial Hospital
Eligibility Criteria
Inclusion Criteria
- •Being \>45 years-of-age,
- •Healthy and physically independent.
Exclusion Criteria
- •The exclusion criteria were individuals on hormone replacement therapy and those with cognitive impairment, progressive debilitating conditions, bone fractures, or any medical contraindications to administering the fitness assessment.
Outcomes
Primary Outcomes
Change from baseline bone mineral density
Time Frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up
Bone mineral density measurement is measured by dual-energy x-ray absorptiometry (DXA). Measurements are made over the lumbar spine and over the upper part of the hip and the measurement is assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Secondary Outcomes
- Triglyceride from blood sample(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Waistline parameters of the subjects(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Change from baseline elbow muscle strength(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- High-density lipoprotein from blood sample(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Change from baseline shoulder muscle strength(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Change from baseline hip muscle strength(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Fasting blood glucose from blood sample(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Blood pressure(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Weight parameters of the subjects(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Height parameters of the subjects(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Change from baseline knee muscle strength(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Change from baseline SF-36 questionnaire assessment(Pre-intervention, 3-month, 6-month, 9-month-follow-up)