Dry Eye Response to Interval Exercise and Mediterranean Diet

Not Applicable

• Conditions: Dry Eye; Physical Inactivity; Diet Habit
• Interventions: Behavioral: lifestyle change; Other: exercise

• Registration Number: NCT05248698
• Lead Sponsor: Cairo University

Brief Summary

in the recent times, dry eye was found to be correlated sedentary life style, obesity, hypertension. So, changing the sedentary lifestyle is recommended

Detailed Description

older patient who will complain from dry eye will be collected. it is planned to recruit 60 elderly (with obesity and hypertension) to be distributed into group 1 (this group will receive 3-time interval exercise per the week, applied for 30 min with high intensity, plus Mediterranean Diet) and group 2 (this group will receive only 3-time interval exercise per the week, applied for 30 min with high intensity). Every group will contain 30 elderly

Study Timeline

• Study Start: 2022-01-05
• Status Verified: 2022-02
• Study First Submitted: 2022-02-07
• Study First Submitted QC: 2022-02-16
• Last Update Submitted: 2022-02-16
• Study First Posted: 2022-02-21
• Last Update Posted: 2022-02-21
• Primary Completion: 2022-12-30
• Study Completion: 2022-12-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• elderly patients with dry eye complaints
• the patients will be obese and hypertensives

Exclusion Criteria

• heart or respiration problems
• other diagnosed eye or systemic diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
group 1	lifestyle change	30 older patient who will complain from dry eye will receive 3-time interval exercise per the week, applied for 30 min with high intensity, plus Mediterranean Diet for 6 months
group 2	exercise	30 older patient who will complain from dry eye will receive 3-time interval exercise per the week, applied for 30 min with high intensity, for 6 months

Primary Outcome Measures

Name	Time	Method
Schirmer's test	6 months	tear-production speed test

Secondary Outcome Measures

Name	Time	Method
Oxford grading system	6 months	a test will examine ocular epithelial damage
Ocular surface disability index	6 months	it is a questionnaire will assess complaints of patients due to severity of dry-eye
blood systole	6 months	it will be measured by sphygmomanometer
blood diastole	6 months	it will be measured by sphygmomanometer
weight	6 months	it will be expressed in kilograms
waist circumference	6 months	it will be evaluated by tape measurements of treatment
tear film break up time testing	6 months	it is a test that will assess tear film stabilization
body mass index	6 months	it will be gained by dividing weight of subject on his or her squared height
scoring system for dry eye	6 months	it is a questionnaire will assess dry-eye severity

Trial Locations

Locations (1)

Cairo Unoversity; 🇪🇬 Giza, Egypt