Epileptic Activity in Patients With Alzheimer's Disease and Lewy Body Dementia
- Conditions
- EpilepsyAlzheimer DiseaseLewy Body Disease
- Registration Number
- NCT04436341
- Lead Sponsor
- Danish Dementia Research Centre
- Brief Summary
In the current study, the investigators will examine the extent of subclinical epileptic activity in patients with Alzheimer's disease and patients with Lewy body dementia as compared to healthy elderly controls. The participants will wear a new device called "ear-EEG", which makes it possible to record EEG for longer periods of time while at home. Furthermore, the investigators want to investigate whether there is an association between subclinical epileptic activity and the cerebral blood flow as measured with functional MRI.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Epileptic activity in patients with Alzheimer's disease and Lewy body dementia as compared to healthy elderly controls 2 years Compare the prevalence and type of paroxysmal activity as measured with the ear-EEG in patients with Alzheimer's disease and Lewy body dementia as compared to healthy elderly controls
Feasibility study: Investigate whether patients with Alzheimer's disease are able wear ear-EEG for longer than 24 hours during a 48 hours period 8 months If it is possible for patients with Alzheimer's disease to wear ear-EEG for at least 24 hours including 5 hours of sleep during a 48 hours period
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Gunhild Waldemar
🇩🇰Copenhagen, Copenhagen OE, Denmark
Troels Wesenberg Kjær
🇩🇰Roskilde, Denmark