跳至主要内容
临床试验/NCT02331576
NCT02331576Unknown不适用

Femoral Nerve Block in Patient With Total Knee Arthroplasty; Analgesic Effect of Perineural Fentanyl Additive to Local Anesthetics

Chonnam National University Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2015年1月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
入组人数
100
试验地点
1
主要终点
Change from baseline in Visual Analogue Scales by time sequence

研究概览

简要总结

The purpose of this study is to evaluate the analgesic efficacy of perineural fentanyl combined with local anesthetics in the post operative pain control with continuous femoral nerve block after total knee arthroplasty.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
60 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients who scheduled to receive knee arthroplasty with general anesthesia
  • ASA physical status 1 or 2

排除标准

  • allergy to drug
  • refuse to the study
  • ASA physical status 3 and 4
  • history of drug abuse
  • cognitive disfunction such as dementia
  • patients who do not adequate for general anesthesia

研究组 & 干预措施

rocaine

Placebo Comparator

continuous femoral nerve block with ropivacaine alone.

干预措施: rocaine (Drug)

rocaine with fentanyl

Active Comparator

continuous femoral nerve block with combination of ropivacaine and fentanyl.

干预措施: rocaine (Drug)

rocaine with fentanyl

Active Comparator

continuous femoral nerve block with combination of ropivacaine and fentanyl.

干预措施: Fentanyl (Drug)

结局指标

主要结局

Change from baseline in Visual Analogue Scales by time sequence

时间窗: baseline(just after operation), 15, 30, 60 minute and 24 hour after intervention

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

BHeo

assistant professor

Chonnam National University Hospital

研究点 (1)

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