The effects of probiotics on bone loss/bone mineral density in early postemenopausal wome

Not Applicable

Active, not recruiting

• Conditions: Osteopenia; Musculoskeletal; Diet and Nutrition - Other diet and nutrition disorders; Musculoskeletal - Osteoporosis

• Registration Number: ACTRN12621000810819
• Lead Sponsor: a Trobe University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-06-28
• Last Update Posted: 26 September 2023

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: Female
• Target Recruitment: 114

Inclusion Criteria

Willingness to participate and availability throughout the study period
- 10-year major fracture risk (based on FRAX score) ranging from 5% in 45-year-old women to 15% in 65-year-old women.
- QUS heel BMD T-score greater than -2.5 standard deviation
- Early postmenopausal women, i.e. < 6 years since menopause
- Signed informed consent to participate to the study

Exclusion Criteria

- QUS heel BMD T-score less than or equal to -2.5 (i.e. potential presence of osteoporosis)
- Normal menstrual cycle or more than 6 years post menopause
- Younger than 45 years old and older than 65 years old.
- Medication that affects BMD
- Presence of disease: diabetes, untreated hyperthyroidismorhypothyroidism, hyperparathyroidism, impaired renal and liver function, malignancy diagnosed during the last 5 years, inflammatory bowel disease, celiac disease, chronic obstructive pulmonary disease, rheumatoid arthritis.
- Smoking or use of nicotine-containing products (currently or during the last six [6] months).
- Alcohol consumption more than 4 units per day.

Study & Design

• Study Type: Interventional
• Study Design: Not specified