A study to compare 2 medical interventions in patients with low egg count to improve outcome of test tube baby treatment
Not Applicable
- Conditions
- Health Condition 1: N978- Female infertility of other origin
- Registration Number
- CTRI/2023/06/053760
- Lead Sponsor
- Oasis centre for Reproductive Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.All poor responders as defined by Poseidon criteria undergoing COS for IVF using antagonist protocol ( AFC less than or equal to 5 , AMH less than or equal to 1.2 ng/dl , unexpected poor response in previous cycle with oocytes retrieved less than or equal to 9)
2.Presence of both ovaries
Exclusion Criteria
1. Any current or past diseases affecting ovaries or gonadotrophin or sex steroid secretion, clearance or excretion
2. Hypogonadotrophic hypogonadism
3. Premature ovarian insufficiency ( FSH > 20 or no AFCs )
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -Total days of stimulation <br/ ><br>-Total dosage of FSH used <br/ ><br>-Number of oocytes retrieved <br/ ><br>-FSH to Oocyte ratio <br/ ><br>-Follicle to oocyte index <br/ ><br>-Follicular output rate <br/ ><br>-M-II rate <br/ ><br>Timepoint: 1 month
- Secondary Outcome Measures
Name Time Method -Fertilisation rate <br/ ><br>-Cleavage rate <br/ ><br>-Blastulation rate <br/ ><br>-Cycle cancellation rate <br/ ><br>-Embryo utilisation rate <br/ ><br>-Implantation rate <br/ ><br>-Biochemical pregnancy rate <br/ ><br>-Clinical pregnancy rate <br/ ><br>-Miscarriage rate <br/ ><br>-Ongoing pregnancy rate <br/ ><br>-Live birth rate <br/ ><br>Timepoint: 1 year