The Validity of Shear Wave Elastography in Diagnosis of Inflammatory and Malignant Pancreatic Diseases
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 主要终点
- shear wave elastography (SWE) in diagnosis of inflammatory and malignant pancreatic diseases
研究概览
简要总结
Only a few studies that have assessed the normal range value for pancreatic stiffness, inflammatory and malignant pancreatic lesions, shear wave velocities of healthy parenchyma, acute and chronic pancreatitis, malignant lesions of the pancreas will be evaluated and compared with other conventional imaging modalities, and evaluate its role in assessment of severity and prediction of clinical course/ outcome in patients with inflammatory pancreatic diseases.
详细描述
The pancreas is a retroperitoneal organ that has several serious inflammatory and malignant diseases can occur, inflammatory diseases include acute and chronic pancreatitis (Janssen et al., 2007).
Acute pancreatitis (AP) is one of the most frequent gastrointestinal causes for hospital admission in the US.
Chronic pancreatitis, although lower in incidence, significantly reduces patients' quality of life (yadav et al., 2013).
Pancreatic cancer has high mortality and is 1 of the top 5 causes of death from cancer. The burden of pancreatic disorders is expected to increase over time (yadav et al., 2013).
AP is an inflammatory condition of the pancreas presenting as abdominal pain and increased levels of pancreatic enzymes in the blood, most commonly caused by bile stones or excessive use of alcohol (Leppäniemi et al., 2019).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Inflammatory pancreatic lesions (acute or chronic pancreatitis)
- •Malignant pancreatic lesions
- •Healthy adult control
排除标准
- •Patient with difficult visualization of the pancreas on B-mode sonography.
- •Patients with acute liver diseases.
- •Obese patient (body mass index >30 kg/m2).
结局指标
主要结局
shear wave elastography (SWE) in diagnosis of inflammatory and malignant pancreatic diseases
时间窗: Baseline
•To measure the shear wave velocity (displayed in kilopascals (kPa) or meters per second) of inflammatory and malignant pancreatic diseases
•To compare the diagnostic success rate of shear wave elastography with other conventional imaging modalities
时间窗: Baseline
•To compare the diagnostic success rate of shear wave elastography with those of sonography and computed tomography (CT) for inflammatory and malignant pancreatic diseases.
次要结局
未报告次要终点
研究者
ZRMohamed
assistant lecturer
Assiut University