The Study of the Neurophysiological Correlation Between Cardiac Neurosis and Anxiety Disorders by Brain Network Analysis Based On Resting State EEG Signals

Phase 1

• Conditions: Cardiac Neurosis , Anxiety Disorders

• Registration Number: ITMCTR2022000066
• Lead Sponsor: Guang'anmen Hospital of Chinese Academy of traditional Chinese medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Group 1:
A: meet the diagnostic criteria of cardiac neurosis;
B. The main syndrome of TCM syndrome differentiation is syndrome of deficiency of Heart, liver and Yin;
C. Meet the diagnostic criteria for panic disorder or generalized anxiety disorder;
D. New outpatient patients who have not received systematic treatment before;
E. Age 18-50, regardless of gender;
F. Right-handed.
Group 2:
A. Meet the diagnostic criteria of cardiac neurosis;
B. The main syndrome of TCM syndrome differentiation is syndrome of deficiency of Heart, liver and Yin;
C. Do not meet the diagnostic criteria for panic disorder or generalized anxiety disorder;
D. New outpatient patients who have not received systematic treatment before;
E. Age 18-50, regardless of gender;
F. Right-handed.
Group 3:
A: meet the diagnostic criteria of panic disorder or generalized anxiety disorder;
B. The main syndrome of TCM syndrome differentiation is syndrome of deficiency of Heart, liver and Yin;
C. Does not meet the diagnostic criteria of cardiac neurosis;
D. New outpatient patients who have not received systematic treatment before;
E. Age 18-50, regardless of gender;
F. Right-handed group: normal control
Group 4:
Hhealthy volunteers without neuropsychiatric and physical diseases, aged 18-50 years old, with no gender limitation; The right hand.

Exclusion Criteria

A. Endocrine and metabolic diseases such as hyperthyroidism;
B. Organic heart disease serious arrhythmia (such as ventricular tachycardia ventricular fibrillation) heart failure;
C. Schizophrenia organic mental disorders Mental disorders due to psychoactive substances or non-addictive substances schizophrenia mood disorders;
D. History of alcohol and drug dependence;
E. Organic brain disease craniocerebral trauma history;
F. Serious organic diseases of liver, kidney and brain;
G.Pregnant and lactating women;
H.Take psychiatric medications or neurological medications for 2 weeks.

Study & Design

• Study Type: Cause/Relative factors study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Brain network connection pattern based on EEG signals;