Optimal value of nasal eosinophil for diagnosis of local allergic rhinitis in common indoor and outdoor aeroallerge
- Conditions
- ocal allergic rhinitisChronic rhinitis,Local allergic rhinitis,eosinophils,nasal cytology,nasal scraping,,non allergic rhinitis ,nasal provocation test
- Registration Number
- TCTR20200309003
- Lead Sponsor
- FACULTY of medicine , C
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 161
1.Clinical chronic rhinitis [runny nose, nasal stuffiness, sneezing]
2.Age 18 yr old and above
3.Negative SPT or IDT or serum specific IgE
.1.Previous use
-antihistamines and/or vasoconstrictors within a week
-intranasal corticosteroid within a month
-systemic corticosteroid within 3 months
2.unstable systemic disease
3.pregnant or lactating women
4.undergone nasal surgery within the previous 3 months
5.chronic rhinosinusitis and/or nasal polyps (confirmed by rigid endoscopy, paranasal x ray, and/or computed tomography)
6.exposed to chemical irritants or cigarette smoke
7. Respiratory tract infection within 4 wks
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method asal eosinophil count At the beginning of study eosinophil count from nasal scrapping
- Secondary Outcome Measures
Name Time Method Cytokine[IgE] At the beginning of study immunocap[PCR],nasal imflammatory cells At the beginning of study cell count for nasal scrapping