Analgesic Efficacy of Different Nerve Blocks in Postoperative Cesarean Section

Not Applicable

Recruiting

• Conditions: Post Operative Pain
• Interventions: Drug: intrathecal morphine for intrathecal morphine group . bupivacaine 0.25% for Quadratus Lumborum and Erector Spinae nerve block groups .

• Registration Number: NCT06088420
• Lead Sponsor: Assiut University

Brief Summary

comparing analgesic efficacy of different nerve blocks on post operative cesarean sections.

Detailed Description

Analgesic efficacy of Erector Spinae, Quadratus Lumborum and Intrathecal Morphine for post operative pain relief after cesarean section,

Study Timeline

• Study First Submitted: 2023-10-10
• Study Start: 2023-10-15
• Study First Submitted QC: 2023-10-15
• Study First Posted: 2023-10-18
• Status Verified: 2025-04
• Primary Completion: 2025-04-05
• Study Completion: 2025-04-05
• Last Update Submitted: 2025-04-06
• Last Update Posted: 2025-04-09

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 120

Inclusion Criteria

• 18-40 years old
• more or equal 37 weeks of gestation
• ASA 1,2
• Elective cesarean delivery

Exclusion Criteria

• Patient refusal
• inability to cooperate with or understand the study
• local infection.
• bleeding disorder
• known anaphylaxis to any drug used in the trial
• ASA physical status more than 2
• emergency operations
• chronic opioid use (opioid use in the past 3 months)
• Neurologic deficit or disorder
• contraindication to regional anesthesia.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intrathcal Morphine Group	intrathecal morphine for intrathecal morphine group . bupivacaine 0.25% for Quadratus Lumborum and Erector Spinae nerve block groups .	Intrathecal morphine administration for post operative pain relief after cesarean section
Quadratus Lumborum nerve block group	intrathecal morphine for intrathecal morphine group . bupivacaine 0.25% for Quadratus Lumborum and Erector Spinae nerve block groups .	Quadratus Lumborum nerve block administration for post operative pain relief after cesarean section
Erector Spinae nerve block group	intrathecal morphine for intrathecal morphine group . bupivacaine 0.25% for Quadratus Lumborum and Erector Spinae nerve block groups .	Erector Spinae nerve block administraion for post operative pain relief after cesarean section

Primary Outcome Measures

Name	Time	Method
Duration of analgesia until first analgesic request.	24 hours .	the time interval from immediate postoperative period until NRS reached 4

Trial Locations

Locations (1)

Mahmoud Mamdouh Ekram; 🇪🇬 Assiut, Manfalout, Egypt