Explorative Study of the Association of Oropharyngeal Microbiota Profiles with SARS-CoV-2 Infection and COVID-19 disease

• Conditions: U07.1; U07.2; COVID-19, virus identified; COVID-19, virus not identified

• Registration Number: DRKS00021424
• Lead Sponsor: German Cancer Research Center (DKFZ)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-06-12
• Study Completion: 2020-12-29
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 356

Inclusion Criteria

Subjects who receive a test for SARS- CoV-2 infection for medical or regulatory reasons.
- Persons who have understood the informed consent and signed the written consent form.

Exclusion Criteria

- Rejection by the patient.
- Age < 18 years.
- Lack of ability to consent.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The main outcome is the association of oropharyngeal microbial diversity and composition with the detection of SARS-CoV-2 in volunteers who have a medical indication for testing for this viral infection.

Secondary Outcome Measures

Name	Time	Method
Microbial diversity and composition in asymptomatic, mild and severe Covid-19 patients<br>Collection of clinical data on mild vs. severe Covid-19 patients