A Hospital-based Prospective Cohort Study With Aged People to Elucidate Predictive Factors Including Muscle and Fat Mass for Chronic Diseases and Mortality

Seoul National University Bundang Hospital1 site in 1 country1,000 target enrollmentJuly 2015

ConditionsAging Sarcopenia

Overview

Phase: N/A
Intervention: Not specified
Conditions: Aging
Sponsor: Seoul National University Bundang Hospital
Enrollment: 1000
Locations: 1
Primary Endpoint: Alll cause mortality
Status: Completed
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study is a hospital-based, prospective cohort study to elucidate the predictive factors including muscle and fat mass for chronic diseases and mortality in elderly persons aged 60 years and older.

Detailed Description

This study is a hospital-based, prospective cohort study to elucidate the predictive factors among anthropometric and biochemical parameters and body composition information for chronic diseases including diabetes mellitus, myocardial infarction, stroke, osteoporosis, fracture, and cognitive dysfunction, and mortality in elderly persons aged 60 years and older.

Registry

clinicaltrials.gov

Start Date

July 2015

End Date

March 15, 2021

Last Updated

5 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Seoul National University Bundang Hospital

Responsible Party

Principal Investigator

Soo Lim

MD, PhD

Seoul National University Bundang Hospital

Eligibility Criteria

Inclusion Criteria

•Aged 60 years and older
•Capable of communication with the research team
•Provided written informed consent

Exclusion Criteria

•Age \< 60 years
•active malignancy
•uncompensated liver cirrhosis
•severe cognitive impairment which cannot communicate with the research term

Outcomes

Primary Outcomes

Alll cause mortality

Time Frame: 9 years

Secondary Outcomes

Cardiometabolic mortality(9 years)
Incidence of major adverse cardiac event including nonfatal myocardial infarction, nonfatal stroke, and unstable angina(9 years)
Incidence of frailty defined by the Korean Fraility Index(9 years)
Incidence of osteoporotic fracture(9 years)
Development of sarcopenia defined by the Foundation for the National Institutes of Health (FNIH) criteria(9 years)
Incidence of cognitive dysfunction measured by minimental status examination(9 years)