Clamping the umbilical cord in premature deliveries (CUPID)
- Conditions
- PrematurityPregnancy and Childbirth
- Registration Number
- ISRCTN92719670
- Lead Sponsor
- Cork University Maternity Hospital
- Brief Summary
2019 results in https://pubmed.ncbi.nlm.nih.gov/30879732/ (added 30/11/2020)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 45
Neonatal inclusion criteria:
1. Infants born at less than 32 weeks gestational age (from 23+0 weeks’ up to and including 31+6 weeks’ gestational age)
2. Vaginal and Caesarean deliveries
Maternal inclusion criteria:
Informed antenatal consent
Neonatal
1. Major congenital anomaly (defined as those that are at high risk of neonatal death or require postnatal surgery)
2. Monochorionic twins with known or suspected twin to twin transfusion syndrome (TTTS) +/- significant growth discordance (>10%)
3. Hydrops fetalis (any aetiology)
4. Known Rh sensitized pregnancy
5. Cord prolapse
Maternal
1. Inability to obtain informed consent
2. Severe or multiple maternal illnesses, including bleeding from placenta praevia, clinical suspicion of placental abruption or accreta, uterine rupture and other causes of maternal coagulopathy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> Neonatal outcome measure:<br> Brain activity in the newborn infant is measured using electroencephalogram (EEG) and near-infrared spectroscopy (NIRS) 6 and 12 hours post-partum.<br><br> Maternal outcome measure:<br> Maternal hemoglobin is measured at 24-36 hours post-partum.<br>
- Secondary Outcome Measures
Name Time Method