eurobiological underpinnings of cognitive emotion regulation in younger and older adults

• Conditions: 10002861; anxiety; stress

• Registration Number: NL-OMON40649
• Lead Sponsor: niversiteit Leiden

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 120

Inclusion Criteria

(a) presence of anxiety disorder
(b) age between 18 and 75 years

Exclusion Criteria

(a) depressieve stoornis
(b) severe role impairments on various life domains
(c) other severe psychiatric disorders

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Behavioural measures: Affective states on the emotion regulation task and<br /><br>reaction times on working memory task. Imaging: Blood-Oxygen-Level Dependent<br /><br>(BOLD) response during the task; BOLD response during rest (functional<br /><br>connectivity); Diffusion tensor imaging (DTI) (structural connectivity).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Exploratory analyses will be done on functional and structural connectivity<br /><br>using fMRI during rest and DTI respectively. Moreover, eye-tracking will be<br /><br>used to measure participants* fixation patterns while watching the visual<br /><br>stimuli. </p><br>