Word-Retrieval for Aphasia: Facilitation of Generalization
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 110
- 试验地点
- 2
- 主要终点
- Word Retrieval Accuracy
研究概览
简要总结
The purpose of this investigation is to further develop and test a treatment for word-finding problems in aphasia. The treatment is designed to strengthen meaning associations within categories of words (e.g., animals, tools, fruits). The treatment is also designed to be used as a search strategy in instances of word-finding difficulty. The study was devised to evaluate the extent to which treatment increases the ability to recall trained, as well as untrained, words.
详细描述
The purpose of the proposed research is to examine the effects of a semantically-oriented treatment on word retrieval in persons with aphasia. The planned investigations are designed to further the development of semantic feature training so that it may serve as not only a mechanism for improving disrupted lexical semantic processing, but also as a compensatory strategy during word retrieval failures. The proposed research will also address the issue of exemplar typicality (Kiran & Thompson, 2003) by examining the effects of training typical versus atypical exemplars of various categories with individuals with different types of aphasia. A series of 24 single subject experimental designs will be conducted in the context of a group design to address the following experimental questions:
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Will training atypical examples of living and artifact noun categories using semantic feature training result in a significantly different outcome* than training typical examples of living and artifact noun categories?
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Will training of one category of nouns using semantic feature training result in improved retrieval of untrained categories of nouns?
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Will effects of semantic feature training vary across aphasia types?
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Will semantic feature training result in increased production of content during discourse?
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Will generalization to untrained typical examples vary across generalization lists that are repeatedly exposed and those that are limited in exposure? (i.e., Does repeated exposure appear to contribute to generalization?)
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Outcome measure will reflect acquisition, response generalization within category, and response generalization across category effects of treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Diagnosis of Wernicke's, Broca's, or Conduction aphasia with significant word-retrieval deficits
- •At least 6 months post-onset of single, left-hemisphere stroke
- •Minimum of high-school education
- •Visual and auditory acuity sufficient for experimental tasks
- •Nonverbal intelligence within normal limits
排除标准
- •Diagnosed mental illness other than depression
- •Neurological condition other than that which resulted in aphasia
- •History of alcohol or substance abuse
- •Non-native English speaker
- •Premorbid history of speech/language disorder
结局指标
主要结局
Word Retrieval Accuracy
时间窗: End of treatment and at 6 weeks post treatment
Accuracy of naming of pictured treated and untreated items was assessed in probes conducted separate from treatment. Probes were conducted repeatedly throughout the study, from baseline (prior to treatment) to follow-up (6 weeks following treatment). All naming responses were scored using a 0-10 scale reflecting promptness and presence of errors; scores of 8-10 received an "accuate" score and scores of 0-7 received an "inaccurate" score. A percentage accuracy score was calculated for each experimental set of items for every probe session. Baseline probe scores were compared to end of treatment and follow-up probe scores to obtain individual effect sizes for each experimental list of items for each participant (i.e., several effect sizes were calculated for each participant). All effect sizes were utlized to obtain an average effect size for each participant; these averages were then utlized to obtain a group average.
次要结局
未报告次要终点