Dead Space Effect of an Anaesthesia Gas Reflector (AnaConDa)
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Region Skane
- Enrollment
- 6
- Locations
- 2
- Primary Endpoint
- Airway Dead Space With Devices for Heat and Moisture Exchange of Respiratory Gas.
Study Overview
Brief Summary
The anesthesia gas reflector (AnaConDa) is built on the adsorptive capacity of active carbon which also adsorbs carbon dioxide in exhaled air. Rebreathing of carbon dioxide thus occurs and must be compensated for by increased ventilation. This study aims at determining how much compensation must be given, based on the hypothesis that rebreathing depends on carbon dioxide level in blood and exhaled air.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Basic Science
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •elective coronary artery by-pass graft surgery
- •elective valve replacement surgery
- •normal left ventricular ejection fraction on preoperative echocardiography
Exclusion Criteria
- •obstructive lung disease
- •restrictive lung disease
Outcomes
Primary Outcomes
Airway Dead Space With Devices for Heat and Moisture Exchange of Respiratory Gas.
Time Frame: 1 hour
A conventional heat and moisture exchanger used in a respiratory circuit during anasthesia was exchanged by an AnaConDa. The AnaConDa causes re-breathing of carbon dioxide which clinically is equivalent to an increased airway dead space. The total airway dead space effect of the AnaConDa, i.e. volume of the device plus rebreathing from the charcoal filter was measured using the Single Breath Test for carbon dioxide, as was airway deadspace of the conventional Heat and Moisture Exchanger. Airway dead space differences between devices was calculated by subtraction of volumes thus achieved. Difference= Airway dead space AnaConDa - Airway dead space conventional Heat and Moisture Exchanger.
Secondary Outcomes
No secondary outcomes reported