The efficacy of testosterone gel application for increases the sperm concentration in infertile men with oligospermia and low serum testosterone level
Phase 4
Completed
- Conditions
- infertile men with oligospermia and low serum testosterone level
- Registration Number
- TCTR20161030001
- Lead Sponsor
- Faculty of Medicine, Siriraj Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Male
- Target Recruitment
- 16
Inclusion Criteria
1.Infertile men with oligospermia (sperm concentration < 15 millions/ml.)
2.low serum testosterone level (<3 ng/ml.)
3.Age > 18 years old
Exclusion Criteria
1.Contraindication to study drug eg. prostatic cancer and breast cancer
2.Allergy to the study drug
3.Secondary cause of oligospermia include hydrocele, varicocele , hypogonadotropic hypogonadism and history of surgery at the testes
4.Previous used of testosterone replacement therapy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method sperm concentration Every month semen analysis
- Secondary Outcome Measures
Name Time Method sperm volume ,sperm motility , sperm morphology, serum testosterone and testosterone/estrogen ratio Every month semen analysis , serum testosterone