Comparison of Quadratus Lumborum Block With Medical Management for Pain Control After Lumbar Spine Fusion Surgery
Overview
- Phase
- Phase 3
- Intervention
- Multimodal Pharmacological Management
- Conditions
- Pain
- Sponsor
- University of Massachusetts, Worcester
- Enrollment
- 9
- Locations
- 1
- Primary Endpoint
- Opioid Consumption
- Status
- Terminated
- Last Updated
- 9 months ago
Overview
Brief Summary
This study will compare the quality of analgesia and reduction of opioid use, between standard of care and two groups of local anesthetic blocks in different location in the quadratus lumborum plane, for postoperative pain control after lumbar spinal fusion and if it reduces opioid consumption.
Detailed Description
This study is a pilot study as part of planning for a larger randomized controlled trial. The study plans to enroll a total of 30 patients, with 10 patients randomly assigned in each group of the study. Group I will receive the standard of care multimodal pharmacological management. Group II will receive standard of care multimodal pharmacological management plus the Quadratus Lumborum II local anesthetic block. Group III will receive standard of care multimodal pharmacological management plus the Quadratus Lumborum III local anesthetic block. Measurements of opioid use, pain, and side effects will be recorded for each patient.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adult Patients undergoing lumbar spinal fusion surgery.
- •Patients from 40-80 years.
Exclusion Criteria
- •Recent drug abuse
- •History of illicit drug use
- •Chronic pain patients not related to the back lesions.
- •Opioid tolerant patients.
- •Patients with any lower extremity weaknesses or deficits.
- •Patients with American Society of Anesthesiologists (ASA) classification more than
- •Coagulopathy.
- •Infection near or in the area of the block.
- •Pregnant patients.
- •Uncooperative patients who refuse care which directly effects research participation or clinical care.
Arms & Interventions
Group 1 Standard of Care
Group I will receive the standard of care multimodal pharmacological management.
Intervention: Multimodal Pharmacological Management
Group 2 Standard of Care + Quadratus Lumborum Block II
Group II will receive standard of care multimodal pharmacological management plus the Quadratus Lumborum II local anesthetic block.
Intervention: Ropivacaine injection Location 1
Group 2 Standard of Care + Quadratus Lumborum Block II
Group II will receive standard of care multimodal pharmacological management plus the Quadratus Lumborum II local anesthetic block.
Intervention: Multimodal Pharmacological Management
Group 3 Standard of Care + Quadratus Lumborum Block III
Group III will receive standard of care multimodal pharmacological management plus the Quadratus Lumborum III local anesthetic block. We will measure opioid use, pain, and side effects in each patient.
Intervention: Ropivacaine injection Location 2
Group 3 Standard of Care + Quadratus Lumborum Block III
Group III will receive standard of care multimodal pharmacological management plus the Quadratus Lumborum III local anesthetic block. We will measure opioid use, pain, and side effects in each patient.
Intervention: Multimodal Pharmacological Management
Outcomes
Primary Outcomes
Opioid Consumption
Time Frame: 48 hours
Dose of the opioids consumed
Secondary Outcomes
- Pain Scale(48 hours)
- Discharge Opioid Use(2 weeks)
- Number of Participants Experiencing Side Effects(Up to 1 week)