Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Renal Surgery

Not Applicable

Completed

• Conditions: Nerve Block; Laparoscopic Renal Surgery; Pain Management
• Interventions: Drug: Morphine given as IPCA(intravenous patient controlled analgesia); Procedure: single-injection QLB(quadratus lumborum block); Device: Philip CX50 Ultrasound Scanner; Device: PAJUNK StimuLong; Drug: single dose ropivacaine

• Registration Number: NCT02841982
• Lead Sponsor: Cui Xulei

Brief Summary

This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay and incidence of chronic pain,et al. between single-injection QLB(quadratus lumborum block)+ intravenous patient-controlled analgesia (IPCA) and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing laparoscopic renal surgeries.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-07-20
• Study First Submitted QC: 2016-07-20
• Study First Posted: 2016-07-22
• Study Start: 2016-08
• Primary Completion: 2018-11
• Study Completion: 2018-12
• Status Verified: 2019-05
• Last Update Submitted: 2019-05-16
• Last Update Posted: 2019-05-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Age 18-70 yrs
• American Society of Anesthesiologists physical statusⅠ-Ⅲ
• Undergo laparoscopic nephrectomy
• Informed consent

Exclusion Criteria

• A known allergy to the drugs being used
• Coagulopathy, on anticoagulants
• Analgesics intake, history of substance abuse
• Participating in the investigation of another experimental agent
• Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
IPCA	Morphine given as IPCA(intravenous patient controlled analgesia)	postoperative IPCA is given alone
single-injection QLB(quadratus lumborum block)	single-injection QLB(quadratus lumborum block)	Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
single-injection QLB(quadratus lumborum block)	single dose ropivacaine	Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
single-injection QLB(quadratus lumborum block)	Philip CX50 Ultrasound Scanner	Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
single-injection QLB(quadratus lumborum block)	PAJUNK StimuLong	Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
single-injection QLB(quadratus lumborum block)	Morphine given as IPCA(intravenous patient controlled analgesia)	Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)

Primary Outcome Measures

Name	Time	Method
cumulative morphine consumption	within 48 postoperative hours

Secondary Outcome Measures

Name	Time	Method
patient satisfaction with anesthesia	48 hours after surgery	use the Chinese version Bauer questionnaire to assess the patient satisfaction with anesthesia
pruritus score	within 24hour after the surgery
The pain scores determined by the numeric rating scale (NRS, 0-10)	At 0, 2,4, 8, 12, 24 ,48,72hours after the surgery
time of recovery of bowl movement	within the 5 days after surgery
Postoperative hospital length of stay	Up to 6 weeks
nausea and vomiting score	within 24 hours after the surgery
quality of recovery	3days and 5days after surgery	use the self-assessment 15 item QoR scale to assess the patient's recovery
ambulation time	within the 7 days after surgery

Trial Locations

Locations (1)

Xulei CUI; 🇨🇳 Beijing, Beijing, China