Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Renal Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- cumulative morphine consumption
研究概览
简要总结
This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay and incidence of chronic pain,et al. between single-injection QLB(quadratus lumborum block)+ intravenous patient-controlled analgesia (IPCA) and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing laparoscopic renal surgeries.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 17 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-70 yrs
- •American Society of Anesthesiologists physical statusⅠ-Ⅲ
- •Undergo laparoscopic nephrectomy
- •Informed consent
排除标准
- •A known allergy to the drugs being used
- •Coagulopathy, on anticoagulants
- •Analgesics intake, history of substance abuse
- •Participating in the investigation of another experimental agent
- •Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)
研究组 & 干预措施
single-injection QLB(quadratus lumborum block)
Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
干预措施: single-injection QLB(quadratus lumborum block) (Procedure)
single-injection QLB(quadratus lumborum block)
Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
干预措施: Philip CX50 Ultrasound Scanner (Device)
single-injection QLB(quadratus lumborum block)
Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
干预措施: PAJUNK StimuLong (Device)
single-injection QLB(quadratus lumborum block)
Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
干预措施: single dose ropivacaine (Drug)
single-injection QLB(quadratus lumborum block)
Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
干预措施: Morphine given as IPCA(intravenous patient controlled analgesia) (Drug)
IPCA
postoperative IPCA is given alone
干预措施: Morphine given as IPCA(intravenous patient controlled analgesia) (Drug)
结局指标
主要结局
cumulative morphine consumption
时间窗: within 48 postoperative hours
次要结局
- patient satisfaction with anesthesia(48 hours after surgery)
- pruritus score(within 24hour after the surgery)
- The pain scores determined by the numeric rating scale (NRS, 0-10)(At 0, 2,4, 8, 12, 24 ,48,72hours after the surgery)
- ambulation time(within the 7 days after surgery)
- time of recovery of bowl movement(within the 5 days after surgery)
- Postoperative hospital length of stay(Up to 6 weeks)
- nausea and vomiting score(within 24 hours after the surgery)
- quality of recovery(3days and 5days after surgery)
研究者
Cui Xulei
Attending physician
Peking Union Medical College Hospital