Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Renal Surgery
Overview
- Phase
- Not Applicable
- Intervention
- single-injection QLB(quadratus lumborum block)
- Conditions
- Laparoscopic Renal Surgery
- Sponsor
- Cui Xulei
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- cumulative morphine consumption
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay and incidence of chronic pain,et al. between single-injection QLB(quadratus lumborum block)+ intravenous patient-controlled analgesia (IPCA) and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing laparoscopic renal surgeries.
Investigators
Cui Xulei
Attending physician
Peking Union Medical College Hospital
Eligibility Criteria
Inclusion Criteria
- •Age 18-70 yrs
- •American Society of Anesthesiologists physical statusⅠ-Ⅲ
- •Undergo laparoscopic nephrectomy
- •Informed consent
Exclusion Criteria
- •A known allergy to the drugs being used
- •Coagulopathy, on anticoagulants
- •Analgesics intake, history of substance abuse
- •Participating in the investigation of another experimental agent
- •Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)
Arms & Interventions
single-injection QLB(quadratus lumborum block)
Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
Intervention: single-injection QLB(quadratus lumborum block)
single-injection QLB(quadratus lumborum block)
Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
Intervention: Philip CX50 Ultrasound Scanner
single-injection QLB(quadratus lumborum block)
Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
Intervention: PAJUNK StimuLong
single-injection QLB(quadratus lumborum block)
Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
Intervention: single dose ropivacaine
single-injection QLB(quadratus lumborum block)
Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
Intervention: Morphine given as IPCA(intravenous patient controlled analgesia)
IPCA
postoperative IPCA is given alone
Intervention: Morphine given as IPCA(intravenous patient controlled analgesia)
Outcomes
Primary Outcomes
cumulative morphine consumption
Time Frame: within 48 postoperative hours
Secondary Outcomes
- patient satisfaction with anesthesia(48 hours after surgery)
- pruritus score(within 24hour after the surgery)
- The pain scores determined by the numeric rating scale (NRS, 0-10)(At 0, 2,4, 8, 12, 24 ,48,72hours after the surgery)
- ambulation time(within the 7 days after surgery)
- time of recovery of bowl movement(within the 5 days after surgery)
- Postoperative hospital length of stay(Up to 6 weeks)
- nausea and vomiting score(within 24 hours after the surgery)
- quality of recovery(3days and 5days after surgery)