Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Adrenalectomy

Peking Union Medical College Hospital1 site in 1 country25 target enrollmentFebruary 16, 2019

ConditionsPain Management Nerve Block Laparoscopic Adrenalectomy

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Pain Management
Sponsor: Peking Union Medical College Hospital
Enrollment: 25
Locations: 1
Primary Endpoint: pain numeric rating scale (NRS, 0-10)pain score at activity at 12 hours after surgery
Status: Terminated
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This prospective, randomized ,control study aims to compare the analgesic effect,quality of recovery, length of hospital stay ,et al. between single-injection QLB(quadratus lumborum block)+general anesthesia (GA) and general anesthesia (GA) alone in patients undergoing laparoscopic adrenalectomy.

Registry

clinicaltrials.gov

Start Date

February 16, 2019

End Date

May 15, 2019

Last Updated

6 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Peking Union Medical College Hospital

Responsible Party

Principal Investigator

Cui Xulei

Attending physician

Peking Union Medical College Hospital

Eligibility Criteria

Inclusion Criteria

•Age 18-70 yrs
•American Society of Anesthesiologists physical statusⅠ-Ⅲ
•Undergo laparoscopic adrenalectomy
•Informed consent

Exclusion Criteria

•A known allergy to the drugs being used
•Coagulopathy, on anticoagulants
•Analgesics intake, history of substance abuse
•Participating in the investigation of another experimental agent
•Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)

Outcomes

Primary Outcomes

pain numeric rating scale (NRS, 0-10)pain score at activity at 12 hours after surgery

Time Frame: At 12hours after the surgery

Secondary Outcomes

The pain scores at rest determined by the numeric rating scale (NRS, 0-10)(At 2,4, 8, 12,24 ,48,72hours after the surgery)
The pain scores at activity determined by the numeric rating scale (NRS, 0-10)(At 2,4, 8, 24 ,48,72hours after the surgery)
incidence of postoperative nausea and vomiting (PONV)(within 24 postoperative hours)
ambulation time(within5 days after surgery)
time of restart anal exhaust(within 5 days after surgery)
Postoperative length of hospital stay(up to2 weeks after surgery)
patient's satisfaction with anesthesia and analgesia(48 hours after surgery)