Transmuscular Quadratus Lumborum Block for Postoperative Pain After Laparoscopic Partial Nephrectomy: A Randomized Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- single-injection TQLB(transmuscular quadratus lumborum block)
- Conditions
- Laparoscopic Renal Surgery
- Sponsor
- Cui Xulei
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- cumulative morphine consumption 8 hours after surgery
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay，et al. between single-injection QLB(quadratus lumborum block)+ intravenous patient-controlled analgesia (IPCA) and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing laparoscopic partial nephrectomy.
Investigators
Cui Xulei
attending physician
Peking Union Medical College Hospital
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •A known allergy to the drugs being used
- •Coagulopathy, on anticoagulants
- •Analgesics intake, history of substance abuse
- •Participating in the investigation of another experimental agent
- •Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)
Arms & Interventions
single-injection TQLB(transmuscular quadratus lumborum block)
Single-injection of TQLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
Intervention: single-injection TQLB(transmuscular quadratus lumborum block)
single-injection TQLB(transmuscular quadratus lumborum block)
Single-injection of TQLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
Intervention: Morphine given as IPCA(intravenous patient controlled analgesia)
Control
postoperative IPCA is given alone
Intervention: Morphine given as IPCA(intravenous patient controlled analgesia)
Outcomes
Primary Outcomes
cumulative morphine consumption 8 hours after surgery
Time Frame: at the 8 hours after surgery
Secondary Outcomes
- cumulative morphine consumption at other time points after surgery(at 0, 2, 4, 12, 24 and 48 hours after surgery)
- episodes of nausea and vomiting(within 24 hours after the surgery)
- quality of recovery evaluated by the self-assessment 15-item quality of recovery (QoR) scale(at 72 hours and 120 hours after the sugery)
- ambulation time(within the 5 days after surgery)
- The pain scores(at rest or on activity) determined by the numeric rating scale (NRS, 0-10)(at 0, 2, 4, 8,12, 24, 48 and 72 hours after surgery)
- time of recovery of bowl movement(within the 5 days after surgery)
- patient satisfaction with anesthesia(at 48 hours after surgery)
- postoperative length of hospital stay(within 2 weeks after the surgery)