Transmuscular Quadratus Lumborum Block for Postoperative Pain After Laparoscopic Partial Nephrectomy: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- cumulative morphine consumption 8 hours after surgery
研究概览
简要总结
This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay，et al. between single-injection QLB(quadratus lumborum block)+ intravenous patient-controlled analgesia (IPCA) and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing laparoscopic partial nephrectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 17 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •A known allergy to the drugs being used
- •Coagulopathy, on anticoagulants
- •Analgesics intake, history of substance abuse
- •Participating in the investigation of another experimental agent
- •Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)
研究组 & 干预措施
single-injection TQLB(transmuscular quadratus lumborum block)
Single-injection of TQLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
干预措施: single-injection TQLB(transmuscular quadratus lumborum block) (Procedure)
single-injection TQLB(transmuscular quadratus lumborum block)
Single-injection of TQLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)
干预措施: Morphine given as IPCA(intravenous patient controlled analgesia) (Drug)
Control
postoperative IPCA is given alone
干预措施: Morphine given as IPCA(intravenous patient controlled analgesia) (Drug)
结局指标
主要结局
cumulative morphine consumption 8 hours after surgery
时间窗: at the 8 hours after surgery
次要结局
- cumulative morphine consumption at other time points after surgery(at 0, 2, 4, 12, 24 and 48 hours after surgery)
- episodes of nausea and vomiting(within 24 hours after the surgery)
- quality of recovery evaluated by the self-assessment 15-item quality of recovery (QoR) scale(at 72 hours and 120 hours after the sugery)
- ambulation time(within the 5 days after surgery)
- The pain scores(at rest or on activity) determined by the numeric rating scale (NRS, 0-10)(at 0, 2, 4, 8,12, 24, 48 and 72 hours after surgery)
- time of recovery of bowl movement(within the 5 days after surgery)
- patient satisfaction with anesthesia(at 48 hours after surgery)
- postoperative length of hospital stay(within 2 weeks after the surgery)
研究者
Cui Xulei
attending physician
Peking Union Medical College Hospital