Transmuscular Quadratus Lumborum Block for Postoperative Pain After Laparoscopic Adrenalectomy

Peking Union Medical College Hospital1 site in 1 country72 target enrollmentMay 10, 2019

ConditionsPain Management Nerve Block Laparoscopic Adrenalectomy

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Pain Management
Sponsor: Peking Union Medical College Hospital
Enrollment: 72
Locations: 1
Primary Endpoint: the NRS pain scores on activity 12-hours after surgery
Status: Completed
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This prospective, randomized control study aims to compare the analgesic effect, satisfaction with anesthesia and analgesia between single-injection QLB (quadratus lumborum block)+general anesthesia (GA) and general anesthesia (GA) alone in patients undergoing laparoscopic adrenalectomy.

Registry

clinicaltrials.gov

Start Date

May 10, 2019

End Date

September 2, 2019

Last Updated

6 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Peking Union Medical College Hospital

Responsible Party

Principal Investigator

Cui Xulei

Attending physician

Peking Union Medical College Hospital

Eligibility Criteria

Inclusion Criteria

•Age 18-70 yrs
•American Society of Anesthesiologists physical statusⅠ-Ⅲ
•Undergo laparoscopic adrenalectomy
•Informed consent

Exclusion Criteria

•a known allergy to the medications being used for anesthesia
•coagulopathy or on anticoagulants
•chronic opioid therapy or history of substance abuse
•participating in another RCT
•inability to properly describe postoperative pain to investigators (e.g., language barrier, neuropsychiatric disorder).

Outcomes

Primary Outcomes

the NRS pain scores on activity 12-hours after surgery

Time Frame: 12-hours after surgery

The NRS (a number scale from 0 to 10) is a commonly used pain intensity rating tool

Secondary Outcomes

the pain scores at rest determined by the numeric rating scale (NRS, 0-10)(At 2,4, 8, 12, 24 ,48,72 hours after the surgery)
time of recovery of bowel movement(within 5 days after surgery)
the NRS pain scores on activity after surgery(At 2,4, 8, 24 ,48,72 hours after the surgery)
incidence of postoperative nausea and vomiting (PONV)(within 24 postoperative hours)
patient's satisfaction of anesthesia and analgesia(48 hours after surgery)
ambulation time(within 5 days after surgery)
postoperative length of hospital stay(up to 2 weeks after surgery)