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Opioid Use and Predicting Factors at the Emergency Department

Completed
Conditions
Pain, Acute
Pain
Interventions
Other: Usual care
Registration Number
NCT06072950
Lead Sponsor
Radboud University Medical Center
Brief Summary

Background: Increasing opioid misuse is a worldwide problem. About 10% of opioid misusers are primarily exposed to opioids at the Emergency Department (ED). This study was conducted to determine the feasibility for a clinical trial investigating the effect of Virtual Reality therapy on opioid consumption at the ED.

Methods: Adult patients were included when primarily seen by the Emergency Physician and presenting with a NRS pain score ≥4. Main objective was to identify the target population and evaluate outcome measures to sustain a trial incorporating the Oral Morphine Equivalent (OME) at the ED as the primary endpoint. Primary outcome was mean OME administered at the ED. Secondary outcomes included NRS pain scores, main symptoms and type of analgesics administered at the ED.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
149
Inclusion Criteria
  • Patient ≥16 years admitted to ED and identified by an Emergency Physician (EP)
  • NRS pain score ≥4
  • Patient is willing and able to comply with the study protocol
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Exclusion Criteria
  • Patients initially treated by another physician than the EP.
  • EMV < 14
  • History of dementia, seizures
  • Severe hearing/visual impairment not corrected
  • Headwounds or damaged skin with which comfortable and hygienic use is not possible.
  • Presentation to ED because of chronic pain (≥3 months) exacerbation
  • Chronic opioids use (≥3 months)
Read More

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Patient with NRS pain at rest being 4 or higherUsual carePatient with NRS pain at rest being 4 or higher, primarily treated by emergency physician, internist, or surgeon. All patients receive usual care, no interventions are administered.
Primary Outcome Measures
NameTimeMethod
Opioid usethroughout study participation, up to 8 hours

Opioids use of patients during their stay at Emergency Department (yes/no)

Secondary Outcome Measures
NameTimeMethod
Administered analgesicsthroughout study participation, up to 8 hours

Type and dose of all administered analgesics at Emergency Department.

Numaric rating score anxiety scoresEvery 30 minutes until discharge of patient

NRS anxiety scores

Duration of ED visitthroughout study participation, up to 8 hours

Duration of ED visit

Analgesics prescriptionsthroughout study participation, up to 8 hours

When patient is discharged home prescribed analgesics are registered.

Oral morphine equivalentthroughout study participation, up to 8 hours

Doses of opioids received by a patient during their stay at the ED converted to Oral morphine equivalent (OME)

Pain acceptabilityAsked at moment of admittance and at discharge, up to 6 hours after inclusion

Patient opinion on acceptability of their pain at rest upon admittance and discharge

Patients openness to VRAssessed upon admittance

yes/no question to explore patients willingeness to use VR in their situation

Reason why patients finds pain acceptableAssessed upon admittance

Open question

Patients desire for analgesicsAsked at moment of admittance and at discharge, up to 6 hours after inclusion

yes/no question whether patient desires analgesics

Satisfaction with pain managementAsked at moment of discharge, up to 6 hours after inclusion

On a numaric rating scale

Nurse opinion on patient adequacy of pain reportingAssessed upon admittance

Categorical question: understating - adequate - exaggerating

Numaric rating score pain scores at restEvery 30 minutes until discharge of patient

Including whether this is pre/post analgesics

Trial Locations

Locations (1)

Radboud university medical center

🇳🇱

Nijmegen, Gelderland, Netherlands

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