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Clinical Trials/NCT01693926
NCT01693926
Completed
N/A

Effect of Physical Activity an Stress in Children

University of Lausanne Hospitals1 site in 1 country50 target enrollmentSeptember 2012

Overview

Phase
N/A
Intervention
Not specified
Conditions
Obesity
Sponsor
University of Lausanne Hospitals
Enrollment
50
Locations
1
Primary Endpoint
Change in salivary Cortisol and maximal levels of salivary cortisol in response to the TSST stress test over 2 hours
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The objective of the study is to evaluate the impact of physical activity in obese and nonobese prepubertal children on:

  1. biological stress responses during a psychosocial stress test
  2. snacking and feeling of hunger in response to the same psychosocial stress test
  3. the moderating factor of attachment on the biological stress responses and on snacking

Children will be investigated on one study day during 3.5 hours.

Detailed Description

Hypotheses In this study, 3 primary hypotheses will be tested. 1. Moderate physical activity during 25 min in children decreases the cortisol levels in response to the Trier Social Stress Test TSST-C (for children). 2. Moderate physical activity during 25 min in children decreases the snacking (calorie consumption when corrected for expenditure and switch in quality of food intake) in response to the Trier Social Stress Test TSST-C (for children). 3. A secure attachment will be a moderating factor for the general increase in cortisol and the snacking in response to the psychosocial stress test (Trier Social Stress Test TSST-C). Secondary objectives: 1. To test if the impact of physical activity on stress responses and snacking differs between obese and non-obese children 2. To test the impact of physical activity on the cardiovascular stress reactivity (blood pressure, heart rate) and the perceived stress (scale) in response to the Trier Social Stress Test TSST-C? 3. To test if the stress reactivity and its modulation by physical activity is different in anxious and in impulsives/labile children 4. To test if serious life events and parental worries and parental educational style influence the stress reactivity

Registry
clinicaltrials.gov
Start Date
September 2012
End Date
December 2017
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University of Lausanne Hospitals
Responsible Party
Principal Investigator
Principal Investigator

Jardena Puder

Medin adjoint

University of Lausanne Hospitals

Eligibility Criteria

Inclusion Criteria

  • 7-10 year old children

Exclusion Criteria

  • Severe illness
  • Medications interfering with study

Outcomes

Primary Outcomes

Change in salivary Cortisol and maximal levels of salivary cortisol in response to the TSST stress test over 2 hours

Time Frame: 9 months

Snacking (Caloric intake, corrected for energy expenditure)

Time Frame: 9 months

Measure of caloric intake and measure of choice of high-caloric vs low-caloric food snacking after the TSST stress test

Moderator effect of attachment (4 different attachment categories), i.e. children with a secure attachment will have lower rises in cortisol compared with children in the other 3 attachment categories

Time Frame: 9 months

Cortisol levels after the TSST stress test will be lower in children with secure attachment compared to detached, disorganized or preoccupied children (i.e. the 3 other attachment categories).

Secondary Outcomes

  • Cardiovascular reactivity (changes and maximal levels of blood pressure, heart rate)(9 months)
  • Perceived stress (stress scale from 1-7)(9 months)
  • Moderator effect of obesity (WHO criteria)(9 months)
  • Moderator role of serious life events and parental worries(9 months)

Study Sites (1)

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