Effects of Corneal Anatomical Match Between Donor and Recipient During DALK Surgery on Final Visual and Refractive Outcomes in Patients With KCN
Phase 2
- Conditions
- Keratoconus
- Interventions
- Procedure: After mechanical trephination, horizontal meridian of donor's cornea sutured to horizontal meridian of recipient cornea
- Registration Number
- NCT04130334
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Patients with KCN who undergo cornea transplantation divided to 2 groups:
Group1: After mechanical trephination, horizontal meridian of donor's cornea sutured to horizontal meridian of recipient cornea Group 2: After mechanical trephination, horizontal meridian of donor's cornea sutured to vertical meridian of recipient cornea After suture removal, best corrected visual acuity, refractive error, corneal keratometry, irregularity of corneal surface and high order aberration of two groups will compare
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
- Patients with KCN who undergo DALK surgery
Exclusion Criteria
- Penetrating Keratoplasty surgery
- Other corneal diseases
- dystrophies
- Corneal graft rejection
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description horizontal meridian of donor's cornea sutured to horizontal After mechanical trephination, horizontal meridian of donor's cornea sutured to horizontal meridian of recipient cornea horizontal meridian of donor's cornea sutured to horizontal meridian of recipient cornea
- Primary Outcome Measures
Name Time Method graft astigmatism 14 months Topography
Best corrected visual acuity 14 months Snellen chart
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Ophthalmic Research Center
🇮🇷Tehran, Iran, Islamic Republic of