Effects of Corneal Anatomical Match Between Donor and Recipient During DALK Surgery on Final Visual and Refractive Outcomes in Patients With KCN: a Clinical Trial
试验速览
- 阶段
- 2 期
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- graft astigmatism
研究概览
简要总结
Patients with KCN who undergo cornea transplantation divided to 2 groups:
Group1: After mechanical trephination, horizontal meridian of donor's cornea sutured to horizontal meridian of recipient cornea Group 2: After mechanical trephination, horizontal meridian of donor's cornea sutured to vertical meridian of recipient cornea After suture removal, best corrected visual acuity, refractive error, corneal keratometry, irregularity of corneal surface and high order aberration of two groups will compare
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with KCN who undergo DALK surgery
排除标准
- •Penetrating Keratoplasty surgery
- •Other corneal diseases
- •dystrophies
- •Corneal graft rejection
研究组 & 干预措施
horizontal meridian of donor's cornea sutured to horizontal
horizontal meridian of donor's cornea sutured to horizontal meridian of recipient cornea
干预措施: After mechanical trephination, horizontal meridian of donor's cornea sutured to horizontal meridian of recipient cornea (Procedure)
horizontal meridian of donor's cornea sutured to vertical
horizontal meridian of donor's cornea sutured to vertical meridian of recipient cornea
干预措施: : After mechanical trephination, horizontal meridian of donor's cornea sutured to vertical meridian of recipient cornea (Procedure)
结局指标
主要结局
graft astigmatism
时间窗: 14 months
Topography
Best corrected visual acuity
时间窗: 14 months
Snellen chart
次要结局
未报告次要终点
研究者
Zahra Rabbani Khah
Head of ophthalmic research center
Shahid Beheshti University of Medical Sciences