Postoperative volumetry after hippocampus-sparing epilepsy surgery

• Conditions: G40.2; G40.3; Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures; Generalized idiopathic epilepsy and epileptic syndromes

• Registration Number: DRKS00006313
• Lead Sponsor: niversitätsklinikum Freiburg Klinik für Neurochirurgie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-07-11
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Epilepsy surgery within the temporal lobe sparing the hippocampus

Exclusion Criteria

Missing postoperative MRI data, dual pathology on MRI scan

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Volumetric difference between preoperative and postoperative hippocampus volumes, assessment via voxel-based morphometry three months after surgery

Secondary Outcome Measures

Name	Time	Method
inks between loss of hippocampal volume and neuropsychological deficits, effect of the resection volume on postoperative hippocampal volume loss, evaluation three months after surgery