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Practicality of newly improved Dual knife with water-jet function for gastrointestinal ESD

Not Applicable
Conditions
early gastric cancer, early colorectal cancer
Registration Number
JPRN-UMIN000018039
Lead Sponsor
Keio University, School of Medicine
Brief Summary

All the lesions were successfully treated by mucosal elevation. The median resected specimen size in stomach and colorectum lesions were 37.3mm and 34.0 mm respectively. The mean procedure time in stomach and colorectum lesions were 36 min and 32.3 min respectively. The en bloc resection rates were 100% in both lesions. The median number of endoscopic device changes in stomach and colorectum lesions were three times and four times respectively. No severe adverse events were observed in both lesions.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
10
Inclusion Criteria

Not provided

Exclusion Criteria

1)Patients whose lesions are found to be outside the guideline or expanded criteria for ESD. 2)Severe fibrosis. 3)Patients with hematological abnormality. 4)Severe liver dysfunction, Severe renal dysfunction, Severe heart dysfunction. 5)Patients who are pregnant or lactation. 6)Patients without written informed consent. 7)Lesions which are thought to be difficult to resect by ESD because of unstable positioning of endoscope. 8)Patients who are disqualified for the study by physicians 9)Refusal of the trial entry.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Primary outcome is to verify the feasibility of mucosal elevation.
Secondary Outcome Measures
NameTimeMethod
The secondary outcomes include the procedure time, the en bloc resection rate, the number of endoscopic device changes (endoscopic injection needle, different device), the adverse event rate such as post-operative bleeding and perforation.
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