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Clinical Trials/NCT01285648
NCT01285648
Completed
Not Applicable

APPLICATION OF CONTINUOUS POSITIVE AIRWAY PRESSURE IN POSTOPERATIVE OF LUNG RESECTION

University of Campinas, Brazil1 site in 1 country40 target enrollmentNovember 2007

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Lung Cancer
Sponsor
University of Campinas, Brazil
Enrollment
40
Locations
1
Primary Endpoint
Bubbling drains
Status
Completed
Last Updated
15 years ago

Overview

Brief Summary

The aim of this study was to compare the oxygenation index (OI), dyspnea, and pain scale and evaluate the duration of thoracic drainage and pleural air leaks after lung resection in two groups of patients: chest physiotherapy (CP) patients and combined CP and Continuous Positive Airway Pressure (CPAP) patients.

Detailed Description

In pulmonary resection surgery complications that lead to significant functional losses of the lung parenchyma and alterations in the ventilatory function may trigger retention of secretions, atelectasis, pneumonia and respiratory failure, which prolong the duration of mechanical ventilation and hospitalisation and contribute to the increase in risk of mortality. In this study the oxygenation index (OI), Borg Scale, pain scale and the presence and duration of thoracic drainage was determined in the immediate postoperative (POi) period and in the first and second postoperative (PO1, PO2) days in 40 patients who underwent elective lung resection. Similar to Chest Physiotherapy, the preventive application of CPAP in the postoperative period after lung resection in our study also appeared to be a safe technique, which allowed improved oxygenation without increasing air leaks through the thoracic drains.

Registry
clinicaltrials.gov
Start Date
November 2007
End Date
February 2010
Last Updated
15 years ago
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Sponsor
University of Campinas, Brazil

Eligibility Criteria

Inclusion Criteria

  • medical diagnosis of lung cancer and an indication for lung resection (lobectomy, bilobectomy and pneumonectomy) with posterolateral thoracotomy;
  • aged between 40 and 75 years.

Exclusion Criteria

  • Patients who refused to participate in the survey;
  • lung resection with incisions other than posterolateral;
  • patients who had contraindications to the use of noninvasive ventilation.

Outcomes

Primary Outcomes

Bubbling drains

Time Frame: From immediate postoperative until fifth, along the study, in a total of one year

From the immediate postoperative day until hospital discharge, the presence of chest tubes and the occurrence of air leaks in them as evidenced by the bubbling of the water seal were recorded. The maintenance and removal of drains or their use with wall suction were determined by applying the medical protocol of the institution through the analysis of X-rays and the amount of drained fluid.

Secondary Outcomes

  • Pain score(Reported pain score after lung resection, along the study, during one year)

Study Sites (1)

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