Correlation of Biochemical Indexes and Retinal Hemodynamic in Patients With Different Degrees of Diabetic Retinopathy
- Conditions
- Diabetic Retinopathy
- Interventions
- Diagnostic Test: imaging
- Registration Number
- NCT05902650
- Lead Sponsor
- Mingzhe Cao
- Brief Summary
All OCTA data and biochemical indexes of diabetic patients were acquired. A prediction model of diabetic retinopathy was built, and the random forest method was used to identify sensitive indicators.
- Detailed Description
Diabetic patients at the Department of Ophthalmology of the Seventh Affiliated Hospital of Sun Yat-sen University were selected as research participants. All OCTA data and biochemical indexes were acquired. A prediction model of diabetic retinopathy was built, and the random forest method was used to identify sensitive indicators.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 200
- Clinical diagnosis of diabetes
- various other types of retinal and choroidal disease;
- history of any intraocular surgery or treatment (including intravitreal injection, retinal photocoagulation etc.
- with severe refractive medium opacity that could affect fundus examination.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Group 1 imaging diabetic patients with no diabetic retinopathy Group 3 imaging diabetic patients with moderate and severe nonproliferative diabetic retinopathy Group 2 imaging diabetic patients with mild nonproliferative diabetic retinopathy Group 4 imaging diabetic patients with proliferative diabetic retinopathy
- Primary Outcome Measures
Name Time Method fasting blood glucose (FBG) the time of the patient's first 1 day visit biochemical indexes
OCTA data the time of the patient's first 1 day visit An image of the 3mm×3mm and 6 mm×6 mm macular areas detected by OCTA were captured. Quantitative analysis of vascular density and perfusion density of superficial capillary plexus in the macular area were automatically calculated using built-in software on the device.
glycosylated hemoglobin (HbAlc) the time of the patient's first 1 day visit biochemical indexes
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
The Seventh Affiliated Hospital, Sun Yat-sen University
🇨🇳Shenzhen, Guangdong, China