Expression of Steroid Receptors in Endometrium

Completed

• Conditions: Endometrium

• Registration Number: NCT00436462
• Lead Sponsor: Aristotle University Of Thessaloniki

Brief Summary

Expression of steroid receptors in endometrium during ovarian stimulation.

Detailed Description

The purpose of this study is to examine in stimulated cycles a) whether there is a difference in expression of steroid receptors in stroma and glands of endometrium between different days during the follicular phase b)whether there are secretory changes detected by endometrium histology before ovulation c)whether there is an association between expression of steroid receptors in endometrium and exposure to oestradiol and progesterone during the follicular phase.

Study Timeline

• Study Start: 2005-12
• Study First Submitted: 2007-02-16
• Study First Submitted QC: 2007-02-16
• Study First Posted: 2007-02-19
• Primary Completion: 2007-12
• Study Completion: 2007-12
• Status Verified: 2009-11
• Last Update Submitted: 2009-11-06
• Last Update Posted: 2009-11-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

• Treatment by IUI,
• BMI:18-29KGR/M2,
• No previous ovarian surgery,
• Normal hysterosalpingography,
• Estradiol < 80pg/ml and progesterone < 1.6ng/ml on day 2 of the cycle

Exclusion Criteria

• Endometriosis,
• Severe male factor

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Steroid receptors expression in endometrium during early follicular phase	3 months

Secondary Outcome Measures

Name	Time	Method
In which day:day o+2, day 0+4 or day HCG	1 month

Trial Locations

Locations (1)

Unit of Human Reproduction, 1st Department of Obstetrics & Gynecology, AUTH, Papageorgiou Hospital; 🇬🇷 Thessaloniki, Greece