Effects of Standing and Light-intensity Activity on Ambulatory Blood Pressure and Blood Glucose
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 10
- 主要终点
- Evidence of change in blood pressure following changes in posture and increasing energy expenditure
研究概览
简要总结
This study aims to test the short-term effects of intermittent standing, slow cycling and slow walking, compared to sitting, on continuous blood glucose and ambulatory blood pressure among pre-hypertensive and pre-diabetic adults.
详细描述
This study will enroll 10 adults who will each complete four experimental conditions in random order. Each of the four experimental conditions are as follows: 1) sit continuously for 8 hours in a simulated office environment, 2) break-up sitting time with standing based on set hourly intervals, 3) break-up sitting time with slow-walking on a treadmill desk based on set hourly intervals, 4) increase energy expenditure by slow cycling based on set hourly intervals. Participants will completed each condition one week apart and dietary intake will be standardized by giving participants the same meals during each intervention condition. Study measures will include: anthropometrics (height and weight), blood pressure, fasting glucose, 24-continuous glucose monitoring, full-day ambulatory blood pressure monitoring, cognitive testing (cognitive performance), energy expenditure, physical activity via accelerometer, sleep via accelerometer, and heart rate.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •pre-hypertensive (systolic blood pressure 120-139 mmHg, or diastolic blood pressure 80-89 mmHg)
- •impaired fasting glucose (5.6-6.9 mmil/L)
- •not meeting the physical activity guidelines for adults (>=150 min/wk of moderate-to-vigorous physical activity)
排除标准
- •smoking, pregnancy, known coronary heart disease, orthopedic limitations for performing physical activity, taking medications to control high blood pressure or high blood glucose, special dietary requirements, and being advised by a doctor to avoid prolonged periods of sitting.
结局指标
主要结局
Evidence of change in blood pressure following changes in posture and increasing energy expenditure
时间窗: single-day intervention
Evidence of change in blood glucose following changes in posture and increasing energy expenditure
时间窗: single-day intervention
次要结局
未报告次要终点
研究者
Noe Crespo
Assistant Professor
Arizona State University