Cardiac Index, SVR/SVRI During Weaning From ECC- Data Obtained From Femoral and Radial Artery Transducer

Not Applicable

Not yet recruiting

• Conditions: Coronary Artery Disease; Mitral Valve Disease; Aortic Valve Disease
• Interventions: Device: CO/CI/SVR

• Registration Number: NCT06112561
• Lead Sponsor: George Papanicolaou Hospital

Brief Summary

Swan Ganz catheter-Edwards Lifesciences obtains values of cardiac output/index and systemic vascular resistance/index using the mean artery pressure of either radial or femoral artery.

During weaning from extracorporeal circulation, arterial waveform-derived cardiac output measurements from radial cannulation site is not reliable as compared with measurements obtained from femoral cannulation site.

Detailed Description

50 consecutive cardiac surgical patients undergoing on-pump primary coronary artery bypass, valve replacement or combined surgery are included in the study. Cardiac output is measured sequentially by the arterial pressure waveform analysis method from radial and femoral arterial sites

Study Timeline

• Study First Submitted: 2023-10-22
• Study First Submitted QC: 2023-10-27
• Study First Posted: 2023-11-01
• Status Verified: 2024-01
• Study Start: 2024-01
• Last Update Submitted: 2024-01-13
• Last Update Posted: 2024-01-17
• Primary Completion: 2024-04
• Study Completion: 2024-05

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Coronary artery disease , aortic valve stenosis, aortic valve regurgitation, mitral valve stenosis, mitral valve regurgitation,

Exclusion Criteria

none

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Cardiac output/index/SVR	CO/CI/SVR	Record of CO/CI/SVR before and after weaning form ECC from radial and femoral artery cannula.
Hypotension event	CO/CI/SVR	Prevent of hypotension event calculated from radial/femoral artery cannula

Primary Outcome Measures

Name	Time	Method
Cardiac output	5 minutes after weaning from extracorporeal circulation (ECC)	Measurement of cardiac output from radial and femoral arterial cannula
Systemic Vascular resistance (SVR)	5 minutes after weaning from ECC	Measurement of SVR from femoral and radial arterial cannula
Prediction of hypotension episode (HPI)	5 minutes after weaning from ECC	Measurement of possibility of hypotension episode (HPI) from femoral and radial arterial cannula