To investigate whether the use of blood marker (plasma neutrophil gelatinase-associated lipocalin) can predict the development of subsequent kidney dysfunction in post non-heart surgical patients who are admitted to the intensive care unit

Not Applicable

Completed

• Conditions: Acute kidney injury; Post non-cardiac operation; Renal and Urogenital - Kidney disease; Surgery - Other surgery

• Registration Number: ACTRN12612000596808
• Lead Sponsor: Shum Hoi Ping

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-06-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 155

Inclusion Criteria

1.All emergency and elective post non-cardiac operation patients that required ICU care

2.Expected ICU length of stay >24 hours

Exclusion Criteria

1.Patients with chronic kidney disease stage 5 (Glomerular filtration rate estimated by Modification of Diet in Renal Disease (MDRD) equation of less than 15 ml/min) or those on renal replacement therapy
2.Surgical intervention that included nephrectomy
3.Cannot obtain consent from patients or their relatives

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Occurrence of Acute kidney injury, defined based on Risk, Injury, Failure, Loss and End stage (RIFLE) classification[48 hours from ICU admission]

Secondary Outcome Measures

Name	Time	Method
Requirement of renal replacement therapy (needs of hemofiltration/ hemodiafiltration/ hemodialysis/ continuous renal replacement therapy, based on medical records upon ICU discharge)[During ICU stay];ICU length of stay (based on medical records upon ICU discharge)[Upon ICU discharge];ICU mortality (based on medical records upon ICU discharge)[Upon ICU discharge]