Incidence of post operative mechanical ventilation in major coelomic oncological surgeries in a tertiary care cancer Centre: A prospective observational study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 600
- 试验地点
- 1
- 主要终点
- Incidence of post operative mechanical ventilation in adult patients above 18 years of age undergoing elective major coelomic oncological surgeries at a tertiary referral cancer institute.
研究概览
简要总结
Mechanical ventilation is a useful modality in patients who are not able to maintain the level of ventilation required for gas exchange i.e., oxygenation and carbon dioxide elimination. There are varied indications for mechanical ventilation, one of the most common being management of postoperative patients recovering from anesthesia and medications.
In our institute, a tertiary oncological center, majority surgeries are major oncological surgeries. In the year 2022, our hospital performed 8643 major surgeries of which 3768 were major coelomic oncological surgeries including, 2083 Gastrointestinal, 581 gynecological, 704 thoracic, 400 urological surgeries.Most of these were done under general anesthesia, commonly involving endotracheal intubation.
Usually, most patients get extubated in the operating room at the end of the surgery, however some remain intubated and get shifted to the recovery room on mechanical ventilation for a myriad of reasons, both planned and unplanned.
Patients requiring unplanned post operative invasive mechanical ventilation often have multiple contributing factors including patient factors such as gender, age, ASA grading, functional status and chronic comorbidities; surgical factors such as technique, grade and urgency of surgery; anesthetic factors such as intraoperative ventilation, hemodynamic instability, vasoactive drugs, metabolic abnormalities, use of opioids and neuromuscular blockade, hypothermia, prolonged duration of surgery etc.
These patients are at a higher risk for poor post operative outcomes, prolonged hospital stay and mortality risk.Thus, they pose a huge burden on patient finances and hospital resources.
As very few datasets exist in our patient population, this study is planned to find the incidence as well as identify the causes of post operative mechanical ventilation in major coelomic oncological surgeries.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult with age above 18 years patients undergoing elective major coelomic surgeries- Gynecology, Gastrointestinal, Urology, Thoracic oncological surgeries under General Anesthesia.
排除标准
- •1.Emergency surgeries 2.Pediatric surgeries 3.Cases for which data pertaining to anesthesia records are missing.
结局指标
主要结局
Incidence of post operative mechanical ventilation in adult patients above 18 years of age undergoing elective major coelomic oncological surgeries at a tertiary referral cancer institute.
时间窗: Postoperative until ICU discharge
次要结局
- To identify the incidence of planned vs unplanned post operative mechanical ventilation in elective surgeries(To identify associated risk factors contributing to post operative mechanical ventilation in both planned and unplanned settings at our institute)
研究者
Dr Aparna Chatterjee
Tata Memorial Centre