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Comparative Effects of Using Black Seed and Cumin Seed on BCP of Obese Grade I

Phase 1
Recruiting
Conditions
Obese
Interventions
Dietary Supplement: Cumin Seed (Cuminum Cyminum)
Dietary Supplement: Black Seed ( Nigella Sativa)
Registration Number
NCT05770791
Lead Sponsor
Sehat Medical Complex
Brief Summary

The goal of this Randomized clinical trial is to compare effectiveness of of using black seed (Nigella sativa) and cumin seed (Cuminum cyminum) on Body composition profile of obese grade 1. The primary objective of this study is To compare effectiveness of of using black seed (Nigella sativa) and cumin seed (Cuminum cyminum) on Body composition profile of obese grade 1. Subjects will be given a consent form and after subjects read and sign the informed consent, they would be included in study according to eligibility criteria.

Detailed Description

Obesity is a global pandemic that is associated with high morbidity and mortality. Natural herbs are commonly used for weight reduction and appetite suppression. Worldwide data based on 1698 studies has shown that the global prevalence of obesity has increased from 3.2 to 10.8% in men and from 6.4 to 14.9% in women. Meanwhile, herbal products are marketed for their weight-loss properties, such as Nigella sativa which has been used for centuries to treat rheumatoid arthritis, diabetes, and asthma; recently, the anti-obesity characteristics of N. sativa have also been indicated. The antihyperglycemic activity, inhibition of free radical formation, anti-obesity and anti-inflammatory activity of cumin seed extract have also been reported previously.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
55
Inclusion Criteria
  • Subject having BMI between 30 kg/m2 - 34.5 kg/m2
Exclusion Criteria
  • Subjects having kidney or liver problems
  • Having ulcers in GIT
  • Subjects having hypertension, thyroid, diabetes or cardiovascular disorders
  • Pregnant and lactating mothers
  • Subjects who are using hormonal or anti-obesity medications

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Group BCumin Seed (Cuminum Cyminum)Group B Obese Grade I
Group ABlack Seed ( Nigella Sativa)Group A Obese Grade I
Primary Outcome Measures
NameTimeMethod
Body Composition ProfileChange from baseline at 30th Day

permits a detailed analysis of the body's major structural components like muscle mass, fat, and bone. It is measured in percentage.

Secondary Outcome Measures
NameTimeMethod
BMIChange from Baseline at 30th Day

Body mass index is a value derived from the mass and height of a person. The BMI is defined as the body mass divided by the square of the body height, and is expressed in units of kg/m², resulting from mass in kilograms and height in metres

Trial Locations

Locations (1)

Sehat Medical Complex, Lahore

🇵🇰

Lahore, Punjab, Pakistan

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