Evaluation of intraocular pressure and optical coherence tomography angiography parameters in preeclampsia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Intraocular pressure and OCT angiography parameters.
研究概览
简要总结
The physiological state of pregnancy and its complications like preeclampsia and eclampsia affect the ocular milieu. However, there is no consensus on how preeclampsia and its sequel affect IOP. This has a bearing on understanding the ocular blood flow alterations in preeclampsia and managing glaucoma patients during their pregnancy.
OCT-Angiography (OCT-A) is a non-invasive imaging modality which employs en face reconstruction of OCT combined with motion contrast processing of red blood cells and provides quantifiable parameters for assessing the microcirculation of retina and choroid in various layers. Though both IOP and BP get affected in preeclampsia, there have been very few studies describing OCTA changes in these subjects.
Therefore this study aims to evaluate IOP and OCTA parameters in subjects of preeclampsia to evaluate the intraocular blood flow and management of glaucoma in such patients.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •Pregnant patients of age 18 to 40 years and period of gestation more that 20 weeks.
排除标准
- •Chronic hypertension.
- •Systemic comorbidities likediabetes or coronary artery disease.
- •Obstetric conditions other than preeclampsia like gestational diabetes on medical management, twin pregnancies.
- •History of any ocular surgeries.
结局指标
主要结局
Intraocular pressure and OCT angiography parameters.
时间窗: At baseline
次要结局
- Central corneal thickness & mean ocular perfusion pressure(At baseline)
研究者
Ayush Arya
Guru Nanak Eye Centre