The Role of Oxytocin in Modulating the Effects of Social Feedback on Achieving Personal Goals

Early Phase 1

Completed

• Conditions: Healthy
• Interventions: Drug: oxytocin treatment; Drug: placebo treatment

• Registration Number: NCT02740101
• Lead Sponsor: University of Electronic Science and Technology of China

Brief Summary

To examine potential differential effects of receiving various social feedback on achieving personal goals,and whether oxytocin would modulate these effects.

Detailed Description

In the present study, 62 healthy male participants participated in the double-blind, placebo-controlled experiment. Investigators aimed to test the idea that whether oxytocin would modulate subjective responses during receiving various social reward and social punishment about the future outcomes of pursuing personal goals.

Study Timeline

• Study Start: 2014-11
• Primary Completion: 2015-08
• Study Completion: 2015-10
• Study First Submitted: 2016-03-21
• Study First Submitted QC: 2016-04-14
• Study First Posted: 2016-04-15
• Status Verified: 2017-03
• Last Update Submitted: 2017-03-02
• Last Update Posted: 2017-03-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 62

Inclusion Criteria

• Healthy subjects without past or current psychiatric or neurological disorders.

Exclusion Criteria

• Taking oral contraceptives;
• No history of head injury and medical or psychiatric illness.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
oxytocin nasal spray	oxytocin treatment	subjects administrating oxytocin were divided into experimental group
placebo nasal spray	placebo treatment	subjects administrating placebo were divided into controlled group

Primary Outcome Measures

Name	Time	Method
Rating of Encouragement after receiving specific social feedback	one hour	There're 96 different social feedback totally for four goals which were divided into four runs consisting of 24 different feedback separately for each goal video.Therefore,subjects were instructed to complete the encouragement rating after receiving each specific feedback. To measure the rating,the investigators used the 9-point likert scale in which one refers to the minimum encouragement while nine refers to maximum encouragement.

Secondary Outcome Measures

Name	Time	Method
Rating of Likeability after receiving specific social feedback	one hour	There're 96 social feedback totally for four goals which were divided into four runs consisting of 24 feedback separately for each goal video.Therefore,subjects were instructed to complete the likeability rating after receiving each specific feedback. To measure the rating,the investigators used the 9-point likert scale in which one refers to the minimum likeability while nine refers to maximum likeability.

Trial Locations

Locations (1)

school of life science and technology, University of Electronic Science and Technology of China; 🇨🇳 Chengdu, Sichuan, China