Impact of duration of administration of pre-operative antibiotics to prevent infection after P

Phase 2

Completed

• Conditions: Health Condition 1: N200- Calculus of kidney

• Registration Number: CTRI/2022/04/041857
• Lead Sponsor: Director PGIMER Chandigarh

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2023-06-30
• Last Update Posted: 1 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 90

Inclusion Criteria

1.Patients > 18 years of age

2.Patients with non-staghorn unilateral renal calculi

3.Patients with no indwelling ureteral stent or percutaneous nephrostomy tube in the ipsilateral or contralateral side

4.Patients with sterile mid-stream urine culture at the time of recruitment

5.Patients with a prior positive urine culture (without resistance to fluoroquinolones) in the past, but a sterile urine culture at the time of recruitment

6.Patients without symptoms of UTI, prior to intervention (PNL)

Exclusion Criteria

1.Patients < 18 years of age

2.Patients with immunodeficiency (e.g., HIV-AIDS, uncontrolled diabetes mellitus, immunodeficiency syndromes)

3.Patients with fever before the surgery, regardless of the initiation of pre-operative antibiotics

4.Patients unfit for general anaesthesia

5.Patients with a known potential focus of sepsis elsewhere in the body

6.Patients without the mental capacity to give consent for the procedure

7.Patients unwilling to participate in the trial

Study & Design

• Study Type: Interventional
• Study Design: Not specified