A Comparison of the Effects of Bovine Freeze-dried Amniotic Membrane and Hydrocolloid on Epithelialization After Laser Treatments
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 51
- 试验地点
- 1
- 主要终点
- Epithelization time
研究概览
简要总结
Bovine amniotic membrane may show better efficacy than hydrocolloid dressing.
详细描述
Bovine amniotic membrane as a biological dressing can be applicable to wound after laser treatments. Comparing with hydrocolloid dressing material, which is the most widely used after laser treatment now, amniotic membrane will show better efficacy. Thus, with amniotic membrane, epithelization time will shorten and redness which is usually left after laser will disappear quickly.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Skin lesions treatable by ablative lasers
- •More than two skin lesions of similar size at the same area
- •Available during the study period (2 weeks)
排除标准
- •Taking steroid or nonsteroidal antiinflammatory drug, isotretinoin
- •underlying diabetes mellitus, keloid or any malignancy
研究组 & 干预措施
amniotic membrane dressing
We compare the efficacy of amniotic membrane and hydrocolloid in same subjects to avoid confounders.
干预措施: laser treatments (Procedure)
amniotic membrane dressing
We compare the efficacy of amniotic membrane and hydrocolloid in same subjects to avoid confounders.
干预措施: amniotic membrane application (Other)
Hydrocolloid dressing
Same subjects received amniotic membrane and hydrocolloid dressing at the same time in different wound.
干预措施: laser treatments (Procedure)
Hydrocolloid dressing
Same subjects received amniotic membrane and hydrocolloid dressing at the same time in different wound.
干预措施: hydrocolloid application (Device)
结局指标
主要结局
Epithelization time
时间窗: 2 weeks
time to complete epithelization after wounding
次要结局
- measurements of adverse effects(2 weeks)
- histopathologic analysis(2 weeks)
- Epithelization Scale(2 weeks)
- Photometric measurements(2 weeks)
- Vancouver scar scale(2 weeks)
- Assessment by subjects(2 weeks)