Quality of Life and Dynamic Visual Acuity in Patients With Bilateral Vestibulopathy: the Impact of Covert-saccades
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Vestibular Diseases
- Sponsor
- Hospices Civils de Lyon
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Frequency of covert-saccades
- Status
- Completed
- Last Updated
- 8 months ago
Overview
Brief Summary
Patients with chronic bilateral vestibular hypofunction may suffer from a visual instability during head movement called oscillopsia. Visual consequence of vestibular deficit can lead to a severe impairment of their quality of life. However, correcting saccades during rapid head movement, called covert-saccades, have been more recently identified. These saccades, which occur during the head movement in patients with vestibular hypofunction, present a very short latency. They could compensate for the lack of vestibular-ocular reflex and greatly decrease oscillopsia and visual impairment. The objective of this study is to evaluate the potential functional benefice of these compensatory movements in a population of 20 patients with chronic bilateral areflexia, in a cross-sectional study.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Bilateral Vestibular Hypofunction (BVH) with at least two of the tree following criteria
- •Mean peak slow phase velocity of 5°/s or less in bilateral bithermal (30 and 44°C) caloric irrigations
- •Pathologic Head-impulse test
- •VOR gain of \<0.25 on rotatory chair tests
- •Disorder present for over 6 month
- •Comprehension of the experiments instructions
- •Patient consent
Exclusion Criteria
- •Corrected Visual Acuity lower than 5/10
- •Other conditions leading to oscillopsia or ataxia
- •Oculomotor palsy, ocular instability in primary position
- •Cervical rachis pathology with instability
- •Cochlear Implants
- •Non-stabilized medical disease
- •Pregnant women
- •Patients under tutelage
Outcomes
Primary Outcomes
Frequency of covert-saccades
Time Frame: Day 0
Frequency of covert saccades corresponds to the total amount of covert-saccades divided by the total amount of head impulse tests multiplied by 100.
Secondary Outcomes
- Dynamic visual acuity(day 0)
- Quality of life assessed with the Dizziness Handicap Inventory(Day 0)
- Oscillopsia severity questionnaire score(day 0)
- Latency of covert-saccades(Day 0)