Early detection of breast cancer using markers in nipple aspirate fluid, blood, and tumor material from women with breast cancer compared to healthy women.
Not Applicable
Completed
- Conditions
- <p>Mamma carcinoma, breast cancer, biomarkers, screening</p>10006291
- Registration Number
- NL-OMON28422
- Lead Sponsor
- niversity Medical Center Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 137
Inclusion Criteria
|
Vrouw = 18 jaar oud |
Exclusion Criteria
|
Bilaterale borstverkleining met tepeltransplantatie |
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>To assess the microRNA expression levels in nipple aspiration fluid obtained just before primary surgery. These will be compared to the microRNA expression levels in NAF obtained from healthy controls (which is already available at our department; study NL41845.041.12).</p><br>
- Secondary Outcome Measures
Name Time Method <p>Within patients, to compare microRNA expression in nipple aspiration fluid from the cancerous breast to microRNA expression in:<br /><br>1. tumor material obtained at surgery<br /><br>2. blood<br /><br>3. NAF from the contralateral breast</p><br>