Limited Long Term Survival in Patients After In-hospital Intestinal Failure Requiring Total Parenteral Nutrition
Completed
- Conditions
- Nutrition Disorders
- Registration Number
- NCT02189993
- Lead Sponsor
- Amsterdam UMC, location VUmc
- Brief Summary
The purpose of this study is to determine what the long term survival is after in hospital use of total parenteral nutrition due to intestinal failure.
Earlier studies only followed patients for a maximum of 6 months or included only very specific patients. We were interested in all patients in our hospital and followed them for up to 2 years.
- Detailed Description
Extensive description is not desired
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 437
Inclusion Criteria
- all consecutive patients on TPN
Exclusion Criteria
- patients from the Pediatric and Haematological Departments
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method All cause mortality Up to 1427 days
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie intestinal failure in patients requiring long-term total parenteral nutrition as studied in NCT02189993?
How does the long-term survival rate of patients on total parenteral nutrition in NCT02189993 compare to standard-of-care outcomes for intestinal failure?
Are there specific biomarkers that correlate with improved survival in intestinal failure patients receiving total parenteral nutrition according to NCT02189993?
What are the potential adverse events associated with prolonged total parenteral nutrition use in intestinal failure patients as observed in NCT02189993?
What therapeutic strategies or compounds are being explored as alternatives to total parenteral nutrition for intestinal failure patients in related clinical trials?
Trial Locations
- Locations (1)
Department of Gastroenterology and Hepatology, Small Bowel Unit, VU University Medical Center
🇳🇱Amsterdam, Netherlands
Department of Gastroenterology and Hepatology, Small Bowel Unit, VU University Medical Center🇳🇱Amsterdam, Netherlands