Effects of Whole Body Vibration on Autonomic Function in Healthy Young and Elderly

Not Applicable

Completed

• Conditions: Healthy; Aging
• Interventions: Other: Whole Body Vibration

• Registration Number: NCT03180814
• Lead Sponsor: Universidade Federal de Pernambuco

Brief Summary

Aging causes anatomical and physiological changes in the cardiovascular system and autonomic function with decline in its maximum function. This study aimed to evaluate the acute effects of whole body vibration on cardiovascular system, autonomic function and heart variability in healthy young and elderly. The investigators' hypothesis is that whole body vibration has different effects in young and elderly.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-03-21
• Study First Submitted QC: 2017-06-06
• Study First Posted: 2017-06-08
• Study Start: 2017-07-31
• Primary Completion: 2017-08-31
• Status Verified: 2017-12
• Last Update Submitted: 2017-12-29
• Study Completion: 2017-12-30
• Last Update Posted: 2018-01-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

• Elderly individuals aged between 60 and 80 years
• Young individuals aged between 18 and 30 years
• Able to walk without assistance
• Good understanding to perform the proposed procedures
• Sedentary or low active

Exclusion Criteria

• Body Mass Index (BMI) > 35Kg/m2
• Systolic blood pressure > 140 mmHg or diastolic blood pressure > 90 mmHg (at rest)
• Difficulty adapting to the whole body vibration
• Smoking
• Neuromuscular or degenerative disorders
• Neurological diseases
• Cardiopulmonary comorbidities
• Cardiac arrhythmias
• Osteoarticular disorders
• Use of hormone replacement therapy
• Use medications or supplements known to affect cardiovascular parameters
• Labyrinthitis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Young Group	Whole Body Vibration	Healthy young of both sexes between the ages of 18 and 30 years will perform a whole body vibration session
Elderly Group	Whole Body Vibration	Healthy elderly of both sexes between the ages of 60 and 80 years will perform a whole body vibration session

Primary Outcome Measures

Name	Time	Method
Autonomic Function	Change from Baseline Heart rate variability at 5, 10, 15, 20 and 35 minutes	Heart rate variability will be assessed from 3-channel holter

Secondary Outcome Measures

Name	Time	Method
Parasympathetic modulation	Change from Baseline Parasympathetic modulation at 5, 10, 15, 20 and 35 minutes	Parasympathetic modulation will be assessed from 3-channel holter
Heart Rate	Change from Baseline Heart Rate at 5, 10, 15, 20 and 35 minutes	Non-invasive measures will be assessed from 3-channel holter
Peripheral oxygen saturation	Change from Baseline Peripheral oxygen saturation at 5, 10, 15, 20 and 35 minutes	Non-invasive measures will be assessed from pulse oximeter
Blood pressure	Change from Baseline Blood pressure at 5, 10, 15, 20 and 35 minutes	Non-invasive measures of brachial blood pressure
Sympathovagal Balance	Change from Baseline Sympathovagal balance at 5, 10, 15, 20 and 35 minutes	Sympathovagal Balance will be assessed from 3-channel holter
Adverse effects	Change from Baseline at 20 minutes	Adverse effects reported by volunteers
Sympathetic modulation	Change from Baseline Sympathetic modulation at 5, 10, 15, 20 and 35 minutes	Sympathetic modulation will be assessed from 3-channel holter

Trial Locations

Locations (1)

Federal University of Pernambuco; 🇧🇷 Recife, Pernambuco, Brazil