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Clinical Trials/NCT03180814
NCT03180814
Completed
Not Applicable

Acute Effects of Whole Body Vibration on Autonomic Function in Healthy Young and Elderly

Universidade Federal de Pernambuco1 site in 1 country35 target enrollmentJuly 31, 2017
ConditionsHealthyAging

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Healthy
Sponsor
Universidade Federal de Pernambuco
Enrollment
35
Locations
1
Primary Endpoint
Autonomic Function
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

Aging causes anatomical and physiological changes in the cardiovascular system and autonomic function with decline in its maximum function. This study aimed to evaluate the acute effects of whole body vibration on cardiovascular system, autonomic function and heart variability in healthy young and elderly. The investigators' hypothesis is that whole body vibration has different effects in young and elderly.

Registry
clinicaltrials.gov
Start Date
July 31, 2017
End Date
December 30, 2017
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Helga Cecília Muniz de Souza

Msc

Universidade Federal de Pernambuco

Eligibility Criteria

Inclusion Criteria

  • Elderly individuals aged between 60 and 80 years
  • Young individuals aged between 18 and 30 years
  • Able to walk without assistance
  • Good understanding to perform the proposed procedures
  • Sedentary or low active

Exclusion Criteria

  • Body Mass Index (BMI) \> 35Kg/m2
  • Systolic blood pressure \> 140 mmHg or diastolic blood pressure \> 90 mmHg (at rest)
  • Difficulty adapting to the whole body vibration
  • Neuromuscular or degenerative disorders
  • Neurological diseases
  • Cardiopulmonary comorbidities
  • Cardiac arrhythmias
  • Osteoarticular disorders
  • Use of hormone replacement therapy
  • Use medications or supplements known to affect cardiovascular parameters

Outcomes

Primary Outcomes

Autonomic Function

Time Frame: Change from Baseline Heart rate variability at 5, 10, 15, 20 and 35 minutes

Heart rate variability will be assessed from 3-channel holter

Secondary Outcomes

  • Parasympathetic modulation(Change from Baseline Parasympathetic modulation at 5, 10, 15, 20 and 35 minutes)
  • Heart Rate(Change from Baseline Heart Rate at 5, 10, 15, 20 and 35 minutes)
  • Peripheral oxygen saturation(Change from Baseline Peripheral oxygen saturation at 5, 10, 15, 20 and 35 minutes)
  • Blood pressure(Change from Baseline Blood pressure at 5, 10, 15, 20 and 35 minutes)
  • Sympathovagal Balance(Change from Baseline Sympathovagal balance at 5, 10, 15, 20 and 35 minutes)
  • Adverse effects(Change from Baseline at 20 minutes)
  • Sympathetic modulation(Change from Baseline Sympathetic modulation at 5, 10, 15, 20 and 35 minutes)

Study Sites (1)

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