Psychodynamic Therapy for Treating Panic Disorder

Phase 2

Completed

• Conditions: Panic Disorder
• Interventions: Other: PFPP; Other: ART

• Registration Number: NCT00128388
• Lead Sponsor: Weill Medical College of Cornell University

Brief Summary

This study will determine the effectiveness of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training in treating adults with panic disorder.

Detailed Description

This is a randomized controlled trial of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training, a less active form of treatment in other studies, for adults with primary Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) panic disorder.

Forty nine patients who have signed written consent who have primary DSM-IV panic disorder have been entered into the study. Randomization has been stratified by presence of major depression and use of psychoactive, anti-panic medications. Medications, if present, have been held constant. All patients have received 24 sessions of either psychodynamic psychotherapy, or applied relaxation training for panic disorder. This study is currently closed for recruitment, although final follow-up assessments have yet to be completed.

Study Timeline

• Study Start: 2000-02
• Primary Completion: 2005-01
• Study Completion: 2005-07
• Study First Submitted: 2005-08-05
• Study First Submitted QC: 2005-08-05
• Study First Posted: 2005-08-09
• Status Verified: 2013-06
• Last Update Submitted: 2013-06-26
• Last Update Posted: 2013-06-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 49

Inclusion Criteria

• 18-55 years old
• Primary DSM-IV panic disorder with or without agoraphobia
• Severity 5/8 minimum on the Anxiety Disorders Interview Schedule

Exclusion Criteria

• Psychosis
• Unstable medication dosage
• Unwilling to discontinue ongoing psychotherapy
• Organic mental syndrome
• Substance use or abuse

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1 PFPP	PFPP	Panic Focused Psychodynamic Psychotherapy
2 ART	ART	Applied Relaxation Training

Primary Outcome Measures

Name	Time	Method
PDSS (panic disorder severity scale)	termination, 2, 4, 6, 12 month f/u

Secondary Outcome Measures

Name	Time	Method
SDS (Sheehan disability scale)	termination, 2, 4, 6, 12 month f/u
HARS (Hamilton anxiety rating scale)	termination, 2, 4, 6, 12 month f/u
HDRS (Hamilton depression rating scale)	termination, 2, 4, 6, 12 month f/u

Trial Locations

Locations (1)

Weill Medical College; 🇺🇸 New York City, New York, United States