Efficacy of oil pulling on drug-induced xerostomia
- Conditions
- R68.2Dry mouth, unspecified
- Registration Number
- DRKS00012459
- Lead Sponsor
- niklinik KölnAbteilung für Zahnerhaltung und Parodontologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 26
Minimum age of 18 years
Daily use of at least one drug which has drug-induced xerostomia declared as a side effect in its package insert
xerostomia with minimum level on VAS Skala of 4 to 10
minimum number of four teeth
allergies relating to the ingredients of the products used in the study (oil)
existing or planned pregnancy during the study
current or anamnestic radiation therapy or chemotherapy
treatment with antibiotics prior to the study
current or anamnestic parotid gland tumor
current or anamnestic tumor in regions of the head or neck
current or anamnestic operation of the head or the neck
Sjögren syndrome
other medical causes for xerostomia which are not drug-induced
current daily use of products which palliate the symptoms of xerostomia
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method VAS xerostomic burden investigated by a validated questionnaire at day 0, after use of the first product (day 7), after the washout Phase (day 14) and after use of the second product (day 21).
- Secondary Outcome Measures
Name Time Method