Prosthetic Valve Sweing Ring Injection by Antiboitics Can Affect the Rate of Postoperative Infective Endocarditis?

• Conditions: Prosthetic Valve Endocarditis
• Interventions: Drug: Aminoglycoside

• Registration Number: NCT05455788
• Lead Sponsor: Assiut University

Brief Summary

Follow-up of patients undergoing cardiac valve replacements with prosthetic valve after injection of sewing ring of prosthetic valve with aminoglycoside for prevention of infective endocarditis.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-12-01
• Status Verified: 2022-07
• Study First Submitted: 2022-07-01
• Study First Submitted QC: 2022-07-09
• Last Update Submitted: 2022-07-09
• Study First Posted: 2022-07-13
• Last Update Posted: 2022-07-13
• Primary Completion: 2023-12-01
• Study Completion: 2023-12-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• patients who need cardiac valve replacement for rheumatic or degenerative causes

Exclusion Criteria

• Patients undergoing open heart surgery for any cause other than valve replacement
• patients who are younger than 20 years old.
• Patients undergoing valve repair.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients undergoing Cardiac valve replacement	Aminoglycoside	-

Primary Outcome Measures

Name	Time	Method
number of patients diagnosed with Infective endocarditis post valve replacement	6 months post operative	percentage of post operative clinical and echocardiographic diagnosis of infective endocarditis on prosthetic valve

Trial Locations

Locations (1)

Assiut University; 🇪🇬 Assiut, Egypt