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Clinical Trials/NCT06725680
NCT06725680
Completed
Not Applicable

Retrolaminar Block Versus Erector Spinae Plane Block as Opioid-Free Anesthesia for Enhanced Recovery After Posterior Lumbar Discectomy: A Randomized Trial

Tanta University1 site in 1 country90 target enrollmentDecember 11, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Retrolaminar Block
Sponsor
Tanta University
Enrollment
90
Locations
1
Primary Endpoint
Time to the 1st rescue analgesia
Status
Completed
Last Updated
5 months ago

Overview

Brief Summary

The aim of this study is to compare retrolaminar block and erector spine plane block as opioid-free anesthesia for enhanced recovery after posterior lumbar discectomy.

Detailed Description

Lumbar discectomy is a common procedure for patients who experience leg and back pain due to disc problems. Effective pain management is crucial for timely discharge and successful rehabilitation. Opioid-free anesthesia is a technique that avoids the use of opioids during surgery. Enhanced recovery after surgery (ERAS) pathways are helpful strategies for incorporating opioid-free pain management techniques into clinical practice. Erector spine plane block (ESPB) and retrolaminar block (RLB) are considered to be compartment blocks or interfacial plane blocks. In these approaches, local anesthetics are assumed to penetrate the superior costotransverse ligament and reach the paravertebral space, although the needle tip is not advanced into the paravertebral space.

Registry
clinicaltrials.gov
Start Date
December 11, 2024
End Date
October 7, 2025
Last Updated
5 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mohammed Said ElSharkawy

Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Tanta University

Eligibility Criteria

Inclusion Criteria

  • Age from 18 to 65 years.
  • Both sexes.
  • American Society of Anesthesiology (ASA) physical status I-II.
  • Undergoing elective posterior lumbar discectomy under general anesthesia.

Exclusion Criteria

  • Body mass index (BMI) \>35 kg/m
  • Patients with disturbed mental status.
  • Allergies to the drugs used in the study.
  • Local infection at the puncture site.
  • Cardiac insufficiency.
  • Renal insufficiency.
  • Coagulopathy.
  • Chronic opioid use.

Outcomes

Primary Outcomes

Time to the 1st rescue analgesia

Time Frame: 24 hours postoperatively

Time from end of surgery to first dose of morphine administrated.

Secondary Outcomes

  • Time to discharge(Till the Aldrete score is ≥9 (Up to 3 hours))
  • Recovery time(Till first response to verbal command (Up to 1 hour))
  • Intraoperative fentanyl consumption(Intraoperatively)
  • Total morphine consumption(24 hours postoperatively)
  • Degree of pain(24 hours postoperatively)
  • Length of hospital stay(Till discharge from hospital (Up to 1 week))
  • Incidence of adverse events(24 hours postoperatively)

Study Sites (1)

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